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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4A
All Species:
21.82
Human Site:
S322
Identified Species:
43.64
UniProt:
Q9HCS5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS5
NP_071423.3
686
79059
S322
I
R
Y
K
H
R
Y
S
G
R
T
A
L
Q
M
Chimpanzee
Pan troglodytes
XP_001143134
686
79014
S322
I
R
Y
K
H
R
Y
S
G
R
T
A
L
Q
M
Rhesus Macaque
Macaca mulatta
XP_001101426
686
79083
S322
I
R
Y
K
H
R
Y
S
G
R
T
A
L
Q
M
Dog
Lupus familis
XP_536286
583
66202
K309
F
E
L
R
V
L
G
K
D
C
N
E
T
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P52963
686
78515
S322
I
S
Y
K
H
R
Y
S
G
R
T
A
L
Q
M
Rat
Rattus norvegicus
Q5FVG2
731
81700
R346
I
R
L
G
S
R
F
R
Y
S
G
K
T
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413976
679
78547
S322
I
G
Y
K
H
R
Y
S
G
R
M
S
F
Q
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
S322
L
G
S
K
H
R
Y
S
G
K
T
A
M
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097989
1517
163353
R315
G
S
R
F
R
H
S
R
P
D
K
Q
T
E
K
Honey Bee
Apis mellifera
XP_394927
636
72253
K328
S
P
P
S
G
S
E
K
H
T
V
I
R
R
N
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
T337
K
F
R
Y
S
G
R
T
E
Y
Q
T
L
E
E
Sea Urchin
Strong. purpuratus
XP_784649
1083
122163
Q314
R
T
Q
E
E
A
L
Q
N
S
M
R
L
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
67.4
N.A.
93.4
27.7
N.A.
N.A.
86
N.A.
67.9
N.A.
22.9
38.7
23.3
27.3
Protein Similarity:
100
99.7
98.5
71.4
N.A.
95.9
45.9
N.A.
N.A.
90
N.A.
76.5
N.A.
31.7
54.8
40.3
40.8
P-Site Identity:
100
100
100
0
N.A.
93.3
20
N.A.
N.A.
73.3
N.A.
60
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
33.3
N.A.
N.A.
80
N.A.
86.6
N.A.
6.6
6.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
42
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
0
9
0
9
9
0
9
0
9
0
0
9
0
25
9
% E
% Phe:
9
9
0
9
0
0
9
0
0
0
0
0
9
0
9
% F
% Gly:
9
17
0
9
9
9
9
0
50
0
9
0
0
0
0
% G
% His:
0
0
0
0
50
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
9
0
0
50
0
0
0
17
0
9
9
9
0
0
9
% K
% Leu:
9
0
17
0
0
9
9
0
0
0
0
0
50
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
42
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% N
% Pro:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
9
9
0
50
0
% Q
% Arg:
9
34
17
9
9
59
9
17
0
42
0
9
9
17
9
% R
% Ser:
9
17
9
9
17
9
9
50
0
17
0
9
0
9
0
% S
% Thr:
0
9
0
0
0
0
0
9
0
9
42
9
25
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
42
9
0
0
50
0
9
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _