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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4A
All Species:
21.82
Human Site:
S334
Identified Species:
43.64
UniProt:
Q9HCS5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS5
NP_071423.3
686
79059
S334
L
Q
M
S
R
D
L
S
I
Q
L
P
R
P
D
Chimpanzee
Pan troglodytes
XP_001143134
686
79014
S334
L
Q
M
S
R
D
L
S
I
Q
L
P
R
P
D
Rhesus Macaque
Macaca mulatta
XP_001101426
686
79083
S334
L
Q
M
S
R
D
L
S
I
Q
L
P
R
P
D
Dog
Lupus familis
XP_536286
583
66202
R321
T
S
F
F
F
E
A
R
S
K
T
A
C
K
H
Cat
Felis silvestris
Mouse
Mus musculus
P52963
686
78515
S334
L
Q
M
S
R
D
L
S
I
Q
L
P
R
P
N
Rat
Rattus norvegicus
Q5FVG2
731
81700
T358
T
E
Y
Q
T
T
K
T
N
K
A
R
R
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413976
679
78547
S334
F
Q
M
T
R
D
P
S
I
Q
L
P
R
P
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
T334
M
Q
I
G
R
E
S
T
E
T
L
P
R
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097989
1517
163353
A327
T
E
K
D
A
L
S
A
G
R
S
P
P
A
F
Honey Bee
Apis mellifera
XP_394927
636
72253
F340
R
R
N
P
P
P
I
F
Q
R
T
P
S
R
R
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
K349
L
E
E
N
E
H
R
K
S
A
G
H
R
N
F
Sea Urchin
Strong. purpuratus
XP_784649
1083
122163
V326
L
R
R
P
E
P
Q
V
Q
R
V
P
S
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
67.4
N.A.
93.4
27.7
N.A.
N.A.
86
N.A.
67.9
N.A.
22.9
38.7
23.3
27.3
Protein Similarity:
100
99.7
98.5
71.4
N.A.
95.9
45.9
N.A.
N.A.
90
N.A.
76.5
N.A.
31.7
54.8
40.3
40.8
P-Site Identity:
100
100
100
0
N.A.
93.3
6.6
N.A.
N.A.
80
N.A.
40
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
100
26.6
N.A.
N.A.
86.6
N.A.
66.6
N.A.
26.6
26.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
9
0
9
9
9
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
9
0
42
0
0
0
0
0
0
0
0
42
% D
% Glu:
0
25
9
0
17
17
0
0
9
0
0
0
0
0
0
% E
% Phe:
9
0
9
9
9
0
0
9
0
0
0
0
0
0
17
% F
% Gly:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
0
9
0
0
0
9
0
42
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
9
0
17
0
0
0
9
0
% K
% Leu:
50
0
0
0
0
9
34
0
0
0
50
0
0
0
0
% L
% Met:
9
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
9
0
0
0
0
9
9
% N
% Pro:
0
0
0
17
9
17
9
0
0
0
0
75
9
42
0
% P
% Gln:
0
50
0
9
0
0
9
0
17
42
0
0
0
0
0
% Q
% Arg:
9
17
9
0
50
0
9
9
0
25
0
9
67
17
17
% R
% Ser:
0
9
0
34
0
0
17
42
17
0
9
0
17
9
0
% S
% Thr:
25
0
0
9
9
9
0
17
0
9
17
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _