KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4A
All Species:
17.88
Human Site:
S402
Identified Species:
35.76
UniProt:
Q9HCS5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS5
NP_071423.3
686
79059
S402
K
K
A
K
N
E
N
S
P
D
T
Q
R
S
K
Chimpanzee
Pan troglodytes
XP_001143134
686
79014
S402
K
K
A
K
N
E
N
S
P
D
T
Q
R
S
K
Rhesus Macaque
Macaca mulatta
XP_001101426
686
79083
S402
K
K
A
K
N
E
N
S
P
D
T
Q
R
S
K
Dog
Lupus familis
XP_536286
583
66202
R389
R
P
D
Q
N
V
A
R
S
R
S
K
T
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
P52963
686
78515
S402
K
K
A
K
N
E
N
S
P
D
P
Q
R
S
K
Rat
Rattus norvegicus
Q5FVG2
731
81700
L426
F
S
S
S
G
P
V
L
V
E
T
E
N
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413976
679
78547
S402
N
S
P
E
T
Q
R
S
K
V
S
A
P
W
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Q402
A
E
S
A
S
V
Q
Q
E
K
P
S
A
P
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097989
1517
163353
G395
P
L
P
Q
P
G
M
G
T
I
S
N
N
Y
D
Honey Bee
Apis mellifera
XP_394927
636
72253
S408
R
S
A
P
W
T
Q
S
Q
P
R
G
L
Y
T
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
A417
H
D
T
D
S
S
D
A
L
G
Y
A
S
D
G
Sea Urchin
Strong. purpuratus
XP_784649
1083
122163
S394
R
R
A
H
S
Q
M
S
G
R
E
S
P
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
67.4
N.A.
93.4
27.7
N.A.
N.A.
86
N.A.
67.9
N.A.
22.9
38.7
23.3
27.3
Protein Similarity:
100
99.7
98.5
71.4
N.A.
95.9
45.9
N.A.
N.A.
90
N.A.
76.5
N.A.
31.7
54.8
40.3
40.8
P-Site Identity:
100
100
100
6.6
N.A.
93.3
6.6
N.A.
N.A.
6.6
N.A.
0
N.A.
0
13.3
0
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
26.6
N.A.
N.A.
33.3
N.A.
20
N.A.
13.3
20
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
50
9
0
0
9
9
0
0
0
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
0
0
9
0
0
34
0
0
0
9
9
% D
% Glu:
0
9
0
9
0
34
0
0
9
9
9
9
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
9
9
9
0
9
0
0
9
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
34
34
0
34
0
0
0
0
9
9
0
9
0
0
34
% K
% Leu:
0
9
0
0
0
0
0
9
9
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
42
0
34
0
0
0
0
9
17
0
0
% N
% Pro:
9
9
17
9
9
9
0
0
34
9
17
0
17
9
17
% P
% Gln:
0
0
0
17
0
17
17
9
9
0
0
34
0
0
0
% Q
% Arg:
25
9
0
0
0
0
9
9
0
17
9
0
34
0
0
% R
% Ser:
0
25
17
9
25
9
0
59
9
0
25
17
9
34
9
% S
% Thr:
0
0
9
0
9
9
0
0
9
0
34
0
9
9
9
% T
% Val:
0
0
0
0
0
17
9
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _