KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4A
All Species:
39.7
Human Site:
Y206
Identified Species:
79.39
UniProt:
Q9HCS5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS5
NP_071423.3
686
79059
Y206
T
A
K
S
L
E
M
Y
G
V
D
L
H
P
V
Chimpanzee
Pan troglodytes
XP_001143134
686
79014
Y206
T
A
K
S
L
E
M
Y
G
V
D
L
H
P
V
Rhesus Macaque
Macaca mulatta
XP_001101426
686
79083
Y206
T
A
K
S
L
E
M
Y
G
V
D
L
H
P
V
Dog
Lupus familis
XP_536286
583
66202
G193
Y
A
I
Q
A
E
L
G
D
Y
D
P
Y
K
H
Cat
Felis silvestris
Mouse
Mus musculus
P52963
686
78515
Y206
T
A
K
S
L
E
M
Y
G
V
D
L
H
P
V
Rat
Rattus norvegicus
Q5FVG2
731
81700
Y230
K
A
K
W
L
E
M
Y
G
V
D
M
H
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413976
679
78547
Y206
V
A
K
S
L
E
M
Y
G
V
D
L
H
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Y206
I
A
K
T
L
E
M
Y
G
V
D
L
H
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097989
1517
163353
Y199
K
V
K
W
H
D
M
Y
G
V
D
L
H
P
V
Honey Bee
Apis mellifera
XP_394927
636
72253
Y212
K
V
K
W
L
E
M
Y
G
V
D
L
H
P
V
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Y221
H
A
R
R
L
E
M
Y
G
M
D
V
Y
D
G
Sea Urchin
Strong. purpuratus
XP_784649
1083
122163
Y198
R
A
K
R
L
E
M
Y
G
V
D
L
C
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
67.4
N.A.
93.4
27.7
N.A.
N.A.
86
N.A.
67.9
N.A.
22.9
38.7
23.3
27.3
Protein Similarity:
100
99.7
98.5
71.4
N.A.
95.9
45.9
N.A.
N.A.
90
N.A.
76.5
N.A.
31.7
54.8
40.3
40.8
P-Site Identity:
100
100
100
20
N.A.
100
73.3
N.A.
N.A.
93.3
N.A.
86.6
N.A.
66.6
80
46.6
80
P-Site Similarity:
100
100
100
33.3
N.A.
100
80
N.A.
N.A.
93.3
N.A.
93.3
N.A.
73.3
80
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
84
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
9
0
100
0
0
9
0
% D
% Glu:
0
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
92
0
0
0
0
0
9
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
75
0
9
% H
% Ile:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
0
84
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
84
0
9
0
0
0
0
75
0
0
0
% L
% Met:
0
0
0
0
0
0
92
0
0
9
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
75
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
9
17
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
34
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
17
0
0
0
0
0
0
0
84
0
9
0
9
84
% V
% Trp:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
92
0
9
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _