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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4A
All Species:
35.15
Human Site:
Y221
Identified Species:
70.3
UniProt:
Q9HCS5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS5
NP_071423.3
686
79059
Y221
Y
G
E
N
K
S
E
Y
F
L
G
L
T
P
V
Chimpanzee
Pan troglodytes
XP_001143134
686
79014
Y221
Y
G
E
N
K
S
E
Y
F
L
G
L
T
P
V
Rhesus Macaque
Macaca mulatta
XP_001101426
686
79083
Y221
Y
G
E
N
K
S
E
Y
F
L
G
L
T
P
V
Dog
Lupus familis
XP_536286
583
66202
Y208
T
T
G
Y
V
S
E
Y
R
F
V
P
D
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
P52963
686
78515
Y221
Y
G
E
N
K
S
E
Y
F
L
G
L
T
P
S
Rat
Rattus norvegicus
Q5FVG2
731
81700
Y245
K
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413976
679
78547
Y221
Y
G
E
N
K
S
E
Y
F
L
G
L
T
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Y221
F
G
E
K
Q
A
E
Y
F
L
G
L
T
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097989
1517
163353
Y214
L
G
E
D
S
V
E
Y
F
L
G
L
T
P
S
Honey Bee
Apis mellifera
XP_394927
636
72253
Y227
L
G
E
D
S
V
E
Y
F
L
G
L
T
P
S
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
I236
V
D
A
N
H
L
P
I
E
I
G
V
G
A
V
Sea Urchin
Strong. purpuratus
XP_784649
1083
122163
Y213
V
G
G
D
H
I
E
Y
F
L
G
T
T
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
67.4
N.A.
93.4
27.7
N.A.
N.A.
86
N.A.
67.9
N.A.
22.9
38.7
23.3
27.3
Protein Similarity:
100
99.7
98.5
71.4
N.A.
95.9
45.9
N.A.
N.A.
90
N.A.
76.5
N.A.
31.7
54.8
40.3
40.8
P-Site Identity:
100
100
100
20
N.A.
93.3
40
N.A.
N.A.
93.3
N.A.
73.3
N.A.
66.6
66.6
20
53.3
P-Site Similarity:
100
100
100
20
N.A.
93.3
60
N.A.
N.A.
100
N.A.
93.3
N.A.
73.3
73.3
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
9
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
34
0
0
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
67
0
0
0
84
0
9
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
75
9
0
0
0
0
0
% F
% Gly:
0
75
17
0
9
0
0
0
0
0
92
0
9
0
0
% G
% His:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
9
% I
% Lys:
9
0
0
9
42
0
0
0
0
0
0
0
0
0
17
% K
% Leu:
17
0
0
0
0
9
0
0
0
84
0
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
50
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
9
0
84
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
17
50
0
0
9
0
0
0
0
0
25
% S
% Thr:
9
9
0
0
0
0
0
0
0
0
0
9
84
0
9
% T
% Val:
17
0
0
0
9
17
0
0
0
0
9
9
0
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
42
0
0
9
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _