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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XAB2
All Species:
22.73
Human Site:
S176
Identified Species:
41.67
UniProt:
Q9HCS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS7
NP_064581.2
855
100010
S176
Y
R
R
F
L
K
L
S
P
E
S
A
E
E
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090436
858
100159
V179
V
S
P
A
G
T
L
V
P
Q
S
A
E
E
Y
Dog
Lupus familis
XP_542113
852
99622
S173
Y
R
R
F
L
K
L
S
P
E
S
A
E
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCD2
855
99969
S176
Y
R
R
F
L
K
L
S
P
E
S
A
E
E
Y
Rat
Rattus norvegicus
Q99PK0
855
99979
S176
Y
R
R
F
L
K
L
S
P
E
S
A
E
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090563
838
97844
S167
Y
R
R
Y
L
K
L
S
P
E
N
A
E
E
Y
Zebra Danio
Brachydanio rerio
NP_001038248
851
99277
S171
Y
R
R
Y
L
K
L
S
P
E
N
A
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610891
883
103308
F174
Y
R
R
Y
L
K
L
F
P
E
D
T
E
E
Y
Honey Bee
Apis mellifera
XP_395622
836
98945
A173
F
R
R
Y
L
K
L
A
P
E
D
T
E
E
Y
Nematode Worm
Caenorhab. elegans
NP_491250
855
99529
N183
Y
R
R
Y
L
K
M
N
P
K
A
R
E
D
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002305003
908
106056
D169
Y
R
R
Y
L
M
Y
D
P
S
H
I
E
D
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198226
917
107033
D169
Y
R
R
Y
L
M
Y
D
P
S
H
I
E
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAK5
829
96495
E183
Q
V
H
P
E
D
A
E
D
F
I
E
L
L
V
Conservation
Percent
Protein Identity:
100
N.A.
98.9
98.4
N.A.
98.8
98.9
N.A.
N.A.
N.A.
74.7
81
N.A.
60.8
63.7
48.2
N.A.
Protein Similarity:
100
N.A.
99
99.3
N.A.
99.4
99.5
N.A.
N.A.
N.A.
87.1
90.9
N.A.
78.4
78.9
69.3
N.A.
P-Site Identity:
100
N.A.
46.6
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
86.6
N.A.
73.3
66.6
53.3
N.A.
P-Site Similarity:
100
N.A.
53.3
100
N.A.
100
100
N.A.
N.A.
N.A.
100
100
N.A.
80
86.6
93.3
N.A.
Percent
Protein Identity:
48.5
N.A.
N.A.
48.7
N.A.
50.1
Protein Similarity:
66.3
N.A.
N.A.
66
N.A.
65.2
P-Site Identity:
40
N.A.
N.A.
46.6
N.A.
0
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
8
0
0
8
54
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
16
8
0
16
0
0
16
0
% D
% Glu:
0
0
0
0
8
0
0
8
0
62
0
8
93
77
0
% E
% Phe:
8
0
0
31
0
0
0
8
0
8
0
0
0
0
16
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
16
0
0
0
% I
% Lys:
0
0
0
0
0
70
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
85
0
70
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
93
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
85
85
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
47
0
16
39
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
16
0
0
0
% T
% Val:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
0
0
54
0
0
16
0
0
0
0
0
0
0
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _