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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XAB2 All Species: 18.79
Human Site: Y74 Identified Species: 34.44
UniProt: Q9HCS7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCS7 NP_064581.2 855 100010 Y74 S Y K L W Y R Y L K A R R A Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090436 858 100159 Q78 Y L K A R R A Q V K H R C V T
Dog Lupus familis XP_542113 852 99622 Q78 Y L K A R R A Q V K H R C V T
Cat Felis silvestris
Mouse Mus musculus Q9DCD2 855 99969 Y74 S Y K L W Y R Y L K A R R A Q
Rat Rattus norvegicus Q99PK0 855 99979 Y74 S Y K L W Y R Y L K A R R A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001090563 838 97844 Q72 Y L K Q R R K Q V K R R C V T
Zebra Danio Brachydanio rerio NP_001038248 851 99277 Q76 Y L R E R R K Q V K G K C I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610891 883 103308 Y72 S Y K I W H N Y L R T R R K Q
Honey Bee Apis mellifera XP_395622 836 98945 Q78 Y L R Q R V N Q L K G R C I T
Nematode Worm Caenorhab. elegans NP_491250 855 99529 Y81 S Y K L W Y H Y L K Y R E S T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002305003 908 106056 I73 Y L V E R L D I V R N L P I T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198226 917 107033 I73 Y L R E R L D I V R N L P V T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SAK5 829 96495 Y75 S Y K L W K M Y L R F R T K H
Conservation
Percent
Protein Identity: 100 N.A. 98.9 98.4 N.A. 98.8 98.9 N.A. N.A. N.A. 74.7 81 N.A. 60.8 63.7 48.2 N.A.
Protein Similarity: 100 N.A. 99 99.3 N.A. 99.4 99.5 N.A. N.A. N.A. 87.1 90.9 N.A. 78.4 78.9 69.3 N.A.
P-Site Identity: 100 N.A. 20 20 N.A. 100 100 N.A. N.A. N.A. 20 6.6 N.A. 60 20 66.6 N.A.
P-Site Similarity: 100 N.A. 26.6 26.6 N.A. 100 100 N.A. N.A. N.A. 33.3 33.3 N.A. 80 26.6 73.3 N.A.
Percent
Protein Identity: 48.5 N.A. N.A. 48.7 N.A. 50.1
Protein Similarity: 66.3 N.A. N.A. 66 N.A. 65.2
P-Site Identity: 0 N.A. N.A. 0 N.A. 53.3
P-Site Similarity: 13.3 N.A. N.A. 20 N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 16 0 0 0 24 0 0 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 24 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % G
% His: 0 0 0 0 0 8 8 0 0 0 16 0 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 16 0 0 0 0 0 24 0 % I
% Lys: 0 0 70 0 0 8 16 0 0 70 0 8 0 16 0 % K
% Leu: 0 54 0 39 0 16 0 0 54 0 0 16 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 16 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % P
% Gln: 0 0 0 16 0 0 0 39 0 0 0 0 0 0 31 % Q
% Arg: 0 0 24 0 54 31 24 0 0 31 8 77 31 0 0 % R
% Ser: 47 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 62 % T
% Val: 0 0 8 0 0 8 0 0 47 0 0 0 0 31 0 % V
% Trp: 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 54 47 0 0 0 31 0 47 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _