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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREB
All Species:
26.36
Human Site:
S220
Identified Species:
58
UniProt:
Q9HCU5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCU5
NP_037520.1
417
45468
S220
V
G
R
D
L
K
A
S
V
W
Q
K
D
Q
L
Chimpanzee
Pan troglodytes
XP_515352
493
54100
S296
V
G
R
D
L
K
A
S
V
W
Q
K
D
Q
L
Rhesus Macaque
Macaca mulatta
XP_001088763
519
57081
S322
V
G
R
D
L
K
A
S
V
W
Q
K
N
Q
L
Dog
Lupus familis
XP_540122
418
45950
S221
V
G
W
D
L
K
A
S
V
W
Q
K
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUQ2
417
45419
S220
V
G
W
D
F
K
A
S
V
W
Q
K
D
Q
L
Rat
Rattus norvegicus
Q9WTV0
417
45339
S220
V
G
W
D
F
K
A
S
V
W
Q
K
D
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515477
474
50907
S278
V
R
F
N
H
D
H
S
L
L
A
T
G
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393821
432
48337
K241
A
S
V
A
K
D
G
K
A
F
V
W
N
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786066
442
49178
A246
T
I
S
R
D
Q
K
A
Y
V
W
N
T
K
D
Poplar Tree
Populus trichocarpa
XP_002314804
370
40241
V178
A
F
N
S
D
S
S
V
L
A
V
G
G
E
D
Maize
Zea mays
NP_001169106
417
45353
S220
V
G
W
D
F
K
A
S
V
W
Q
K
D
Q
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
77.8
92.8
N.A.
88.7
89.4
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
32.3
Protein Similarity:
100
82.9
79
95.2
N.A.
93.5
94.2
N.A.
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
N.A.
52.4
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
23.7
89.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.1
94.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
0
0
64
10
10
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
64
19
19
0
0
0
0
0
0
55
0
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
10
10
0
28
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
64
0
0
0
0
10
0
0
0
0
10
19
10
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
64
10
10
0
0
0
64
0
10
0
% K
% Leu:
0
0
0
0
37
0
0
0
19
10
0
0
0
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
10
19
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
64
0
0
64
0
% Q
% Arg:
0
10
28
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
10
0
10
10
73
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% T
% Val:
73
0
10
0
0
0
0
10
64
10
19
0
0
10
0
% V
% Trp:
0
0
37
0
0
0
0
0
0
64
10
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _