Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PREB All Species: 10.3
Human Site: S364 Identified Species: 22.67
UniProt: Q9HCU5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCU5 NP_037520.1 417 45468 S364 R G P E L L G S H E T A L F S
Chimpanzee Pan troglodytes XP_515352 493 54100 S440 R G P E L L G S H E T A L F S
Rhesus Macaque Macaca mulatta XP_001088763 519 57081 S466 R G P E L L G S H E T A L F S
Dog Lupus familis XP_540122 418 45950 F365 R G P E L L G F H E T A L F S
Cat Felis silvestris
Mouse Mus musculus Q9WUQ2 417 45419 P364 C G P K L L G P H E T A L F S
Rat Rattus norvegicus Q9WTV0 417 45339 P364 C G P K L L G P H E T A L F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515477 474 50907 E421 V S C L N V S E S G T F L G L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393821 432 48337 N382 D G P T I A S N T E I A V V S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786066 442 49178 D390 N S R R V V G D K D A A V L S
Poplar Tree Populus trichocarpa XP_002314804 370 40241 T317 K L L A M G M T Q G D V L L V
Maize Zea mays NP_001169106 417 45353 P364 C G P K L L G P H E T A L F S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.7 77.8 92.8 N.A. 88.7 89.4 N.A. 54.6 N.A. N.A. N.A. N.A. N.A. 32.1 N.A. 32.3
Protein Similarity: 100 82.9 79 95.2 N.A. 93.5 94.2 N.A. 63.9 N.A. N.A. N.A. N.A. N.A. 53.4 N.A. 52.4
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. 33.3 N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 N.A. N.A. N.A. N.A. N.A. 53.3 N.A. 46.6
Percent
Protein Identity: 23.7 89.6 N.A. N.A. N.A. N.A.
Protein Similarity: 38.1 94.2 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 80 N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 86.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 0 0 10 82 0 0 0 % A
% Cys: 28 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 10 0 10 10 0 0 0 0 % D
% Glu: 0 0 0 37 0 0 0 10 0 73 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 10 0 64 0 % F
% Gly: 0 73 0 0 0 10 73 0 0 19 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 10 0 0 28 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 10 10 10 64 64 0 0 0 0 0 0 82 19 10 % L
% Met: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 73 0 0 0 0 28 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 37 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 19 0 0 0 0 19 28 10 0 0 0 0 0 82 % S
% Thr: 0 0 0 10 0 0 0 10 10 0 73 0 0 0 0 % T
% Val: 10 0 0 0 10 19 0 0 0 0 0 10 19 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _