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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREB
All Species:
26.67
Human Site:
T149
Identified Species:
58.67
UniProt:
Q9HCU5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCU5
NP_037520.1
417
45468
T149
E
N
L
Q
A
V
Q
T
D
F
S
S
D
P
L
Chimpanzee
Pan troglodytes
XP_515352
493
54100
T225
E
N
L
Q
A
V
Q
T
D
F
S
S
D
P
L
Rhesus Macaque
Macaca mulatta
XP_001088763
519
57081
T251
E
N
L
Q
A
V
Q
T
D
F
S
S
D
P
L
Dog
Lupus familis
XP_540122
418
45950
T150
E
N
L
K
A
V
Q
T
D
F
S
P
D
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUQ2
417
45419
T149
K
N
L
E
A
V
Q
T
D
F
S
N
E
P
L
Rat
Rattus norvegicus
Q9WTV0
417
45339
T149
K
N
L
E
A
V
Q
T
D
F
S
T
E
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515477
474
50907
K218
E
R
G
P
R
Q
R
K
K
P
A
A
T
E
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393821
432
48337
D171
P
L
D
S
V
Q
T
D
F
S
E
V
E
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786066
442
49178
D175
R
L
Q
S
V
Q
T
D
F
S
P
T
D
S
S
Poplar Tree
Populus trichocarpa
XP_002314804
370
40241
V118
Q
L
P
Y
R
M
V
V
H
P
G
G
D
G
V
Maize
Zea mays
NP_001169106
417
45353
T149
K
N
L
E
A
V
Q
T
D
F
S
T
E
P
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
77.8
92.8
N.A.
88.7
89.4
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
32.3
Protein Similarity:
100
82.9
79
95.2
N.A.
93.5
94.2
N.A.
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
N.A.
52.4
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
23.7
89.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.1
94.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
73.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
64
0
0
0
0
0
10
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
19
64
0
0
0
55
0
0
% D
% Glu:
46
0
0
28
0
0
0
0
0
0
10
0
37
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
19
64
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
0
0
10
0
0
0
10
10
0
0
0
0
0
0
% K
% Leu:
0
28
64
0
0
0
0
0
0
0
0
0
0
0
64
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
64
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
0
10
10
0
0
0
0
0
19
10
10
0
73
0
% P
% Gln:
10
0
10
28
0
28
64
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
19
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
19
0
0
0
0
0
19
64
28
0
10
10
% S
% Thr:
0
0
0
0
0
0
19
64
0
0
0
28
10
0
0
% T
% Val:
0
0
0
0
19
64
10
10
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _