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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREB
All Species:
13.64
Human Site:
Y177
Identified Species:
30
UniProt:
Q9HCU5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCU5
NP_037520.1
417
45468
Y177
A
T
G
G
T
D
G
Y
V
R
V
W
K
V
P
Chimpanzee
Pan troglodytes
XP_515352
493
54100
Y253
A
T
G
G
T
D
G
Y
V
R
V
W
K
V
P
Rhesus Macaque
Macaca mulatta
XP_001088763
519
57081
Y279
A
T
G
G
T
D
G
Y
V
R
V
W
K
V
P
Dog
Lupus familis
XP_540122
418
45950
Y178
A
T
G
G
T
D
G
Y
V
R
I
W
K
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUQ2
417
45419
H177
A
T
G
G
T
D
G
H
V
R
V
W
K
V
P
Rat
Rattus norvegicus
Q9WTV0
417
45339
H177
A
T
G
G
S
D
G
H
V
R
V
W
K
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515477
474
50907
D246
A
G
A
E
T
R
Q
D
G
E
E
L
R
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393821
432
48337
H199
V
T
G
G
T
D
G
H
I
R
L
W
K
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786066
442
49178
H203
V
T
G
G
V
D
G
H
I
R
M
W
T
Y
P
Poplar Tree
Populus trichocarpa
XP_002314804
370
40241
D146
D
E
V
K
D
N
E
D
H
K
L
G
L
K
P
Maize
Zea mays
NP_001169106
417
45353
H177
A
T
G
G
T
D
G
H
V
R
V
W
K
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
77.8
92.8
N.A.
88.7
89.4
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
32.3
Protein Similarity:
100
82.9
79
95.2
N.A.
93.5
94.2
N.A.
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
N.A.
52.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
73.3
Percent
Protein Identity:
23.7
89.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.1
94.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
93.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
82
0
19
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
10
0
0
10
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
82
82
0
0
82
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
46
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
19
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
10
0
0
73
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
19
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
91
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
82
0
0
10
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
82
0
0
73
0
0
0
0
0
0
0
10
0
0
% T
% Val:
19
0
10
0
10
0
0
0
64
0
55
0
0
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _