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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREB
All Species:
30.91
Human Site:
Y245
Identified Species:
68
UniProt:
Q9HCU5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCU5
NP_037520.1
417
45468
Y245
P
T
F
S
S
T
P
Y
R
Y
Q
A
C
R
F
Chimpanzee
Pan troglodytes
XP_515352
493
54100
Y321
P
T
F
S
S
T
P
Y
R
Y
Q
A
C
R
F
Rhesus Macaque
Macaca mulatta
XP_001088763
519
57081
Y347
P
T
F
S
S
T
P
Y
R
Y
Q
A
C
R
F
Dog
Lupus familis
XP_540122
418
45950
Y246
P
T
F
S
N
T
P
Y
R
Y
Q
A
C
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUQ2
417
45419
Y245
P
A
S
S
N
T
P
Y
R
Y
Q
A
C
R
F
Rat
Rattus norvegicus
Q9WTV0
417
45339
Y245
P
T
S
S
N
T
P
Y
R
Y
Q
A
C
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515477
474
50907
F303
T
L
E
K
V
L
E
F
R
A
H
T
G
E
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393821
432
48337
Y266
S
P
P
N
G
L
K
Y
M
Y
K
R
C
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786066
442
49178
Y271
E
C
A
D
H
K
S
Y
R
F
G
S
C
R
Y
Poplar Tree
Populus trichocarpa
XP_002314804
370
40241
T203
M
E
I
I
L
N
E
T
Q
A
H
A
S
L
K
Maize
Zea mays
NP_001169106
417
45353
Y245
P
T
S
S
N
T
P
Y
R
Y
Q
A
C
R
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
77.8
92.8
N.A.
88.7
89.4
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
32.3
Protein Similarity:
100
82.9
79
95.2
N.A.
93.5
94.2
N.A.
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
N.A.
52.4
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
46.6
Percent
Protein Identity:
23.7
89.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.1
94.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
93.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
19
0
73
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
82
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
10
0
0
0
19
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
37
0
0
0
0
10
0
10
0
0
0
0
73
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
10
10
0
0
0
10
0
0
0
10
% K
% Leu:
0
10
0
0
10
19
0
0
0
0
0
0
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
37
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
64
10
10
0
0
0
64
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
64
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
82
0
0
10
0
82
0
% R
% Ser:
10
0
28
64
28
0
10
0
0
0
0
10
10
0
0
% S
% Thr:
10
55
0
0
0
64
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
73
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _