Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP13A1 All Species: 13.33
Human Site: S368 Identified Species: 22.56
UniProt: Q9HD20 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HD20 NP_065143.2 1204 132955 S368 K E P I E D L S P D R V L D L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115784 2592 283262 S488 W E P I E D L S P D R V L D L
Dog Lupus familis XP_533862 1206 133185 N370 K E P I E D L N P D R V L D L
Cat Felis silvestris
Mouse Mus musculus Q9EPE9 1200 132360 S365 K E P I E D L S P D R V L D L
Rat Rattus norvegicus NP_001099549 1197 131897 S362 K E P I E D L S P D R V L D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKB7 1204 134040 K319 G E S I P V T K T Q L P Q A D
Frog Xenopus laevis NP_001121351 1174 131204 N330 K E P I E D L N P E N I L D V
Zebra Danio Brachydanio rerio NP_001001403 1177 131112 D334 K E P I E D L D P N R I L D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609490 1225 136418 L373 M K E S L E S L D N L D V E M
Honey Bee Apis mellifera XP_396194 1147 128969 D320 K E P I E E I D G N R Q L D I
Nematode Worm Caenorhab. elegans P90747 1178 131955 E317 K E P I E D V E K D K I F D I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002325729 1188 131624 M324 Q W K V V S I M G R G T E E K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT02 1179 131097 V326 P Q W K V P I V G Q R S D E K
Baker's Yeast Sacchar. cerevisiae P39986 1215 135250 P323 K E S I K L R P S E D N L Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 41.2 96.2 N.A. 94.8 94.5 N.A. N.A. 24.4 76.1 73.7 N.A. 51.8 57.3 52.4 N.A.
Protein Similarity: 100 N.A. 44.1 98 N.A. 96.8 96.6 N.A. N.A. 43.4 84.7 83.9 N.A. 67.7 72.9 68.3 N.A.
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 100 100 N.A. N.A. 13.3 66.6 80 N.A. 0 53.3 53.3 N.A.
P-Site Similarity: 100 N.A. 93.3 100 N.A. 100 100 N.A. N.A. 13.3 93.3 93.3 N.A. 40 80 80 N.A.
Percent
Protein Identity: 44.1 N.A. N.A. 42.7 40.9 N.A.
Protein Similarity: 61.4 N.A. N.A. 61 60.3 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 58 0 15 8 43 8 8 8 65 8 % D
% Glu: 0 79 8 0 65 15 0 8 0 15 0 0 8 22 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 22 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 79 0 0 22 0 0 0 0 22 0 0 15 % I
% Lys: 65 8 8 8 8 0 0 8 8 0 8 0 0 0 15 % K
% Leu: 0 0 0 0 8 8 50 8 0 0 15 0 65 0 50 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 15 0 22 8 8 0 0 0 % N
% Pro: 8 0 65 0 8 8 0 8 50 0 0 8 0 0 0 % P
% Gln: 8 8 0 0 0 0 0 0 0 15 0 8 8 8 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 8 58 0 0 0 0 % R
% Ser: 0 0 15 8 0 8 8 29 8 0 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 8 0 0 8 0 0 0 % T
% Val: 0 0 0 8 15 8 8 8 0 0 0 36 8 0 8 % V
% Trp: 8 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _