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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP13A1 All Species: 50.3
Human Site: Y475 Identified Species: 85.13
UniProt: Q9HD20 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HD20 NP_065143.2 1204 132955 Y475 K D P S R N R Y K L F L E C T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115784 2592 283262 Y639 K D P S R N R Y K L F L E C T
Dog Lupus familis XP_533862 1206 133185 Y477 K D P S R N R Y K L F L E C T
Cat Felis silvestris
Mouse Mus musculus Q9EPE9 1200 132360 Y472 K D P S R N R Y K L F L E C T
Rat Rattus norvegicus NP_001099549 1197 131897 Y469 K D P S R N R Y K L F L E C T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKB7 1204 134040 G425 A L N G E E A G E V V K K A L
Frog Xenopus laevis NP_001121351 1174 131204 Y437 K D P S R N R Y K L F L E C T
Zebra Danio Brachydanio rerio NP_001001403 1177 131112 Y441 K D P S R N K Y K L F L E C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609490 1225 136418 Y480 E D P E R N R Y K L F L E C T
Honey Bee Apis mellifera XP_396194 1147 128969 Y427 E D P T R N R Y K L F L E C T
Nematode Worm Caenorhab. elegans P90747 1178 131955 Y425 V D E T R S K Y K L F L E C T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002325729 1188 131624 Y434 E D P T R S K Y K L F L S C S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT02 1179 131097 Y433 E D P T R S K Y K L L L G C S
Baker's Yeast Sacchar. cerevisiae P39986 1215 135250 S429 T K M G R I Q S K L I L D C I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 41.2 96.2 N.A. 94.8 94.5 N.A. N.A. 24.4 76.1 73.7 N.A. 51.8 57.3 52.4 N.A.
Protein Similarity: 100 N.A. 44.1 98 N.A. 96.8 96.6 N.A. N.A. 43.4 84.7 83.9 N.A. 67.7 72.9 68.3 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 0 100 93.3 N.A. 86.6 86.6 66.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 20 100 100 N.A. 93.3 100 86.6 N.A.
Percent
Protein Identity: 44.1 N.A. N.A. 42.7 40.9 N.A.
Protein Similarity: 61.4 N.A. N.A. 61 60.3 N.A.
P-Site Identity: 60 N.A. N.A. 53.3 33.3 N.A.
P-Site Similarity: 93.3 N.A. N.A. 86.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % C
% Asp: 0 86 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 29 0 8 8 8 8 0 0 8 0 0 0 72 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 79 0 0 0 0 % F
% Gly: 0 0 0 15 0 0 0 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % I
% Lys: 50 8 0 0 0 0 29 0 93 0 0 8 8 0 0 % K
% Leu: 0 8 0 0 0 0 0 0 0 93 8 93 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 65 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 79 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 93 0 58 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 50 0 22 0 8 0 0 0 0 8 0 15 % S
% Thr: 8 0 0 29 0 0 0 0 0 0 0 0 0 0 72 % T
% Val: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 86 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _