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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRS2
All Species:
23.94
Human Site:
T246
Identified Species:
58.52
UniProt:
Q9HD23
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HD23
NP_065713.1
443
50318
T246
K
S
L
S
E
L
E
T
D
I
K
I
F
K
E
Chimpanzee
Pan troglodytes
XP_001171606
443
50332
T246
K
S
L
S
E
L
E
T
D
I
K
I
F
K
E
Rhesus Macaque
Macaca mulatta
XP_001100770
443
50129
T246
K
S
L
S
E
L
E
T
D
I
K
I
F
K
E
Dog
Lupus familis
XP_545367
420
47558
F228
L
E
T
D
I
K
I
F
K
E
S
V
L
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCE8
434
49281
T237
K
S
L
S
E
L
E
T
D
I
K
I
F
K
E
Rat
Rattus norvegicus
Q9ET09
434
49347
T237
K
S
L
S
E
L
E
T
D
I
K
I
F
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418911
432
49137
T235
K
S
L
S
E
L
E
T
D
L
K
V
F
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693621
422
47813
S230
L
H
M
L
L
L
N
S
K
S
L
S
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02783
413
47064
L221
C
K
G
V
L
Q
D
L
E
F
S
I
T
R
D
Red Bread Mold
Neurospora crassa
Q7SFQ9
547
61536
K337
R
V
L
L
V
L
S
K
R
V
S
T
F
E
Q
Conservation
Percent
Protein Identity:
100
99.5
97.2
82.1
N.A.
83
84.6
N.A.
N.A.
71.3
N.A.
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.4
88.2
N.A.
89.8
89.6
N.A.
N.A.
80.8
N.A.
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
86.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23
25.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.7
42.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
60
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
60
0
60
0
10
10
0
0
10
20
70
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
0
70
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
50
0
60
0
0
10
% I
% Lys:
60
10
0
0
0
10
0
10
20
0
60
0
0
60
0
% K
% Leu:
20
0
70
20
20
80
0
10
0
10
10
0
10
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% R
% Ser:
0
60
0
60
0
0
10
10
0
10
30
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
60
0
0
0
10
10
0
0
% T
% Val:
0
10
0
10
10
0
0
0
0
10
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _