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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPSECS All Species: 27.27
Human Site: S102 Identified Species: 50
UniProt: Q9HD40 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HD40 NP_001153200.1 501 55726 S102 I G R S G D I S A V Q P K A A
Chimpanzee Pan troglodytes XP_517129 500 55575 S102 I G R S G D I S A V Q P K A A
Rhesus Macaque Macaca mulatta XP_001082141 501 55587 S102 I G R S G D I S A V Q P K A A
Dog Lupus familis XP_545970 525 57970 S123 I G R S G D I S A V Q P K A A
Cat Felis silvestris
Mouse Mus musculus Q6P6M7 504 55307 S102 I G R S G D I S A V Q P K A A
Rat Rattus norvegicus NP_001121759 504 55313 S102 I G R S G D I S A V Q P K A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026329 489 53823 S102 I G R S G D I S A V Q P K A A
Frog Xenopus laevis NP_001093359 506 55694 A102 I G R S G D I A A I Q P K A A
Zebra Danio Brachydanio rerio Q803A7 490 53711 A102 I G R S G D I A A V Q P K A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649556 478 53173 L102 I G R S G D L L E A Q P K A A
Honey Bee Apis mellifera XP_625123 508 55821 E102 I G R S S D L E E V Q P K A A
Nematode Worm Caenorhab. elegans Q18953 481 53390 L96 I G R S G N L L E I Q P K A L
Sea Urchin Strong. purpuratus XP_781218 481 53532 R100 H G L F S A A R F S F T L L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.4 88 N.A. 87.3 86.7 N.A. N.A. 80.8 77 72.8 N.A. 45.1 51.7 41.1 60
Protein Similarity: 100 99.8 99.1 92 N.A. 94 94.2 N.A. N.A. 89.8 88.5 85.4 N.A. 64.8 71 60.2 75.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 86.6 93.3 N.A. 73.3 73.3 60 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 80 80 80 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 8 16 70 8 0 0 0 93 85 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 24 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 0 100 0 0 85 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 93 0 0 0 0 0 70 0 0 16 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 93 0 8 % K
% Leu: 0 0 8 0 0 0 24 16 0 0 0 0 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 93 0 0 0 0 % Q
% Arg: 0 0 93 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 93 16 0 0 54 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _