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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPSECS
All Species:
32.12
Human Site:
T389
Identified Species:
58.89
UniProt:
Q9HD40
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HD40
NP_001153200.1
501
55726
T389
E
H
R
D
K
A
V
T
Q
L
G
S
M
L
F
Chimpanzee
Pan troglodytes
XP_517129
500
55575
T389
E
H
R
D
K
A
V
T
Q
L
G
S
M
L
F
Rhesus Macaque
Macaca mulatta
XP_001082141
501
55587
T389
E
H
H
D
E
A
V
T
Q
L
G
S
M
L
F
Dog
Lupus familis
XP_545970
525
57970
T410
E
H
Q
D
K
A
I
T
Q
L
G
S
M
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6M7
504
55307
T389
G
H
H
D
K
A
V
T
Q
L
G
S
M
L
F
Rat
Rattus norvegicus
NP_001121759
504
55313
T389
G
H
Q
D
R
A
V
T
Q
L
G
S
M
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026329
489
53823
T389
E
N
N
D
A
A
V
T
Q
L
G
S
M
L
F
Frog
Xenopus laevis
NP_001093359
506
55694
T389
E
Q
S
G
S
A
V
T
Q
L
G
S
M
L
F
Zebra Danio
Brachydanio rerio
Q803A7
490
53711
T389
A
H
S
S
S
A
V
T
Q
L
G
S
M
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649556
478
53173
A381
A
I
T
L
A
T
L
A
G
D
Q
M
K
S
I
Honey Bee
Apis mellifera
XP_625123
508
55821
V388
H
Q
H
D
N
K
Q
V
T
M
L
G
L
M
L
Nematode Worm
Caenorhab. elegans
Q18953
481
53390
G382
P
A
K
Q
T
L
F
G
S
I
L
F
A
K
G
Sea Urchin
Strong. purpuratus
XP_781218
481
53532
E387
G
D
G
K
A
L
T
E
L
G
S
M
L
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
88
N.A.
87.3
86.7
N.A.
N.A.
80.8
77
72.8
N.A.
45.1
51.7
41.1
60
Protein Similarity:
100
99.8
99.1
92
N.A.
94
94.2
N.A.
N.A.
89.8
88.5
85.4
N.A.
64.8
71
60.2
75.4
P-Site Identity:
100
100
86.6
86.6
N.A.
86.6
80
N.A.
N.A.
80
73.3
73.3
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
93.3
N.A.
N.A.
86.6
73.3
73.3
N.A.
6.6
26.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
24
70
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
62
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
47
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
70
% F
% Gly:
24
0
8
8
0
0
0
8
8
8
70
8
0
0
8
% G
% His:
8
54
24
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
8
8
31
8
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
0
0
8
0
16
8
0
8
70
16
0
16
70
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
16
70
8
0
% M
% Asn:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
16
8
0
0
8
0
70
0
8
0
0
0
0
% Q
% Arg:
0
0
16
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
16
8
16
0
0
0
8
0
8
70
0
8
0
% S
% Thr:
0
0
8
0
8
8
8
70
8
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
62
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _