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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPSECS All Species: 47.27
Human Site: Y310 Identified Species: 86.67
UniProt: Q9HD40 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HD40 NP_001153200.1 501 55726 Y310 I Q E I S K M Y P G R A S A S
Chimpanzee Pan troglodytes XP_517129 500 55575 Y310 I Q E I S K M Y P G R A S A S
Rhesus Macaque Macaca mulatta XP_001082141 501 55587 Y310 I Q E I S K M Y P G R A S A S
Dog Lupus familis XP_545970 525 57970 Y331 I Q E I S K M Y P G R A S A S
Cat Felis silvestris
Mouse Mus musculus Q6P6M7 504 55307 Y310 I Q D I S K M Y P G R A S A S
Rat Rattus norvegicus NP_001121759 504 55313 Y310 I Q E I S K M Y P G R A S A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026329 489 53823 Y310 I Q E I S K M Y P G R A S A S
Frog Xenopus laevis NP_001093359 506 55694 Y310 V Q E I S K M Y P G R A S A S
Zebra Danio Brachydanio rerio Q803A7 490 53711 Y310 I Q E I S K I Y P G R A S A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649556 478 53173 V302 V A S F N E S V L H D V A S T
Honey Bee Apis mellifera XP_625123 508 55821 Y309 L D R I S K M Y P G R A S A S
Nematode Worm Caenorhab. elegans Q18953 481 53390 Y303 I Q S I A Q S Y P G R A S S V
Sea Urchin Strong. purpuratus XP_781218 481 53532 Y308 M D R I G Q T Y P G R A S A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.4 88 N.A. 87.3 86.7 N.A. N.A. 80.8 77 72.8 N.A. 45.1 51.7 41.1 60
Protein Similarity: 100 99.8 99.1 92 N.A. 94 94.2 N.A. N.A. 89.8 88.5 85.4 N.A. 64.8 71 60.2 75.4
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 100 93.3 93.3 N.A. 0 80 60 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 40 86.6 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 0 0 0 0 0 93 8 85 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 8 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 62 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 93 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 70 0 0 93 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % P
% Gln: 0 77 0 0 0 16 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 16 0 0 0 0 0 0 0 93 0 0 0 0 % R
% Ser: 0 0 16 0 77 0 16 0 0 0 0 0 93 16 85 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % T
% Val: 16 0 0 0 0 0 0 8 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _