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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF3
All Species:
26.97
Human Site:
S194
Identified Species:
45.64
UniProt:
Q9HD45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HD45
NP_064508.3
589
67888
S194
T
K
I
Q
M
S
Y
S
V
K
W
K
K
S
D
Chimpanzee
Pan troglodytes
XP_507954
607
70225
S212
T
K
I
Q
M
S
Y
S
V
K
W
K
K
S
D
Rhesus Macaque
Macaca mulatta
XP_001101439
587
67524
S192
T
K
I
Q
M
S
Y
S
V
K
W
K
K
S
D
Dog
Lupus familis
XP_849773
587
67524
S192
T
K
I
Q
M
S
Y
S
V
K
W
K
K
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET30
587
67526
S192
T
K
I
Q
M
S
Y
S
V
K
W
K
K
S
D
Rat
Rattus norvegicus
Q4KLL4
643
74657
N235
C
T
L
P
E
G
A
N
S
L
P
Q
E
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519976
578
66876
S183
T
K
I
Q
M
S
Y
S
V
K
W
K
K
S
D
Chicken
Gallus gallus
XP_421629
557
64535
V170
V
K
W
K
K
S
D
V
K
F
E
D
R
F
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998554
586
67695
S191
T
R
I
P
M
S
Y
S
V
K
W
K
K
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647979
592
67790
E197
S
H
I
N
F
S
Y
E
V
N
W
K
P
S
K
Honey Bee
Apis mellifera
XP_623945
586
67800
E191
T
A
I
S
F
S
Y
E
V
N
W
K
K
S
N
Nematode Worm
Caenorhab. elegans
NP_500130
580
66626
E185
A
E
L
T
F
T
Y
E
V
Q
W
S
K
S
E
Sea Urchin
Strong. purpuratus
XP_785201
582
67244
Q187
I
K
I
P
F
T
Y
Q
I
T
W
K
K
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04562
672
76328
L270
T
T
G
K
P
L
I
L
D
E
D
K
D
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
99.3
98.9
N.A.
98.9
34.3
N.A.
90.4
93.2
N.A.
92.8
N.A.
72.6
75.3
68.5
74
Protein Similarity:
100
93.7
99.3
99.3
N.A.
99.1
53.5
N.A.
92
93.8
N.A.
95.4
N.A.
83.6
86.2
80.9
84.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
20
N.A.
86.6
N.A.
46.6
60
33.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
33.3
N.A.
93.3
N.A.
53.3
66.6
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
0
8
8
8
0
65
% D
% Glu:
0
8
0
0
8
0
0
22
0
8
8
0
8
0
15
% E
% Phe:
0
0
0
0
29
0
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
72
0
0
0
8
0
8
0
0
0
0
8
0
% I
% Lys:
0
58
0
15
8
0
0
0
8
50
0
79
72
0
8
% K
% Leu:
0
0
15
0
0
8
0
8
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
15
0
0
0
8
8
% N
% Pro:
0
0
0
22
8
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
0
0
0
43
0
0
0
8
0
8
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
0
8
0
72
0
50
8
0
0
8
0
79
0
% S
% Thr:
65
15
0
8
0
15
0
0
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
8
72
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
79
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _