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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF3
All Species:
31.82
Human Site:
S421
Identified Species:
53.85
UniProt:
Q9HD45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HD45
NP_064508.3
589
67888
S421
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Chimpanzee
Pan troglodytes
XP_507954
607
70225
S439
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Rhesus Macaque
Macaca mulatta
XP_001101439
587
67524
S419
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Dog
Lupus familis
XP_849773
587
67524
S419
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET30
587
67526
S419
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Rat
Rattus norvegicus
Q4KLL4
643
74657
Q476
Y
Y
F
G
F
R
K
Q
P
Y
D
N
P
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519976
578
66876
S410
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Chicken
Gallus gallus
XP_421629
557
64535
S389
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998554
586
67695
S418
T
I
L
G
R
N
L
S
G
Q
P
N
F
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647979
592
67790
D424
T
V
V
G
R
N
L
D
G
Q
P
D
F
P
C
Honey Bee
Apis mellifera
XP_623945
586
67800
A418
T
I
L
G
R
N
L
A
G
T
P
D
A
P
C
Nematode Worm
Caenorhab. elegans
NP_500130
580
66626
A412
T
V
I
G
R
N
M
A
G
S
A
D
Y
P
C
Sea Urchin
Strong. purpuratus
XP_785201
582
67244
A414
T
I
L
G
R
A
L
A
G
Q
P
N
H
P
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04562
672
76328
C505
S
I
V
A
H
K
Q
C
N
W
D
E
H
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
99.3
98.9
N.A.
98.9
34.3
N.A.
90.4
93.2
N.A.
92.8
N.A.
72.6
75.3
68.5
74
Protein Similarity:
100
93.7
99.3
99.3
N.A.
99.1
53.5
N.A.
92
93.8
N.A.
95.4
N.A.
83.6
86.2
80.9
84.2
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
N.A.
100
N.A.
73.3
73.3
46.6
80
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
N.A.
100
N.A.
93.3
86.6
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
22
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
86
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
15
22
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
65
0
0
% F
% Gly:
0
0
0
93
0
0
0
0
86
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
79
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
72
0
0
0
79
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
79
0
0
8
0
0
72
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
79
0
8
93
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
72
0
0
0
0
0
% Q
% Arg:
0
0
0
0
86
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
0
0
0
0
0
58
0
8
0
0
0
0
0
% S
% Thr:
86
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
0
15
15
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _