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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF3
All Species:
50.3
Human Site:
Y272
Identified Species:
85.13
UniProt:
Q9HD45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HD45
NP_064508.3
589
67888
Y272
D
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Chimpanzee
Pan troglodytes
XP_507954
607
70225
Y290
D
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Rhesus Macaque
Macaca mulatta
XP_001101439
587
67524
Y270
D
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Dog
Lupus familis
XP_849773
587
67524
Y270
D
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET30
587
67526
Y270
D
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Rat
Rattus norvegicus
Q4KLL4
643
74657
S326
I
E
D
T
M
E
E
S
G
W
K
L
V
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519976
578
66876
Y261
D
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Chicken
Gallus gallus
XP_421629
557
64535
D248
G
W
K
Q
V
H
G
D
V
F
R
P
S
S
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998554
586
67695
Y269
D
R
D
P
G
D
E
Y
G
W
K
Q
V
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647979
592
67790
Y275
E
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Honey Bee
Apis mellifera
XP_623945
586
67800
Y269
E
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Nematode Worm
Caenorhab. elegans
NP_500130
580
66626
Y263
D
A
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Sea Urchin
Strong. purpuratus
XP_785201
582
67244
Y265
E
R
D
L
G
D
E
Y
G
W
K
Q
V
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04562
672
76328
S355
D
N
E
F
H
E
D
S
G
W
K
L
G
H
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
99.3
98.9
N.A.
98.9
34.3
N.A.
90.4
93.2
N.A.
92.8
N.A.
72.6
75.3
68.5
74
Protein Similarity:
100
93.7
99.3
99.3
N.A.
99.1
53.5
N.A.
92
93.8
N.A.
95.4
N.A.
83.6
86.2
80.9
84.2
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
100
0
N.A.
93.3
N.A.
93.3
93.3
93.3
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
100
13.3
N.A.
93.3
N.A.
100
100
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
0
86
0
0
79
8
8
0
0
0
0
0
0
0
% D
% Glu:
22
8
8
0
0
15
86
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
0
79
0
8
0
93
0
0
0
8
0
93
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
93
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
93
0
0
0
0
% K
% Leu:
0
0
0
72
0
0
0
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
79
0
0
0
% Q
% Arg:
0
72
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
15
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
8
0
0
0
86
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
93
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _