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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO10 All Species: 19.09
Human Site: S1575 Identified Species: 30
UniProt: Q9HD67 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HD67 NP_036466.2 2058 237347 S1575 E A I K I F N S L Q Q L E S M
Chimpanzee Pan troglodytes XP_001175408 2253 258494 S1773 E A I K I F N S L Q Q L E S M
Rhesus Macaque Macaca mulatta XP_001087868 2196 251859 P1736 R S C R L P L P S G C Q G E L
Dog Lupus familis XP_546379 2223 252049 S1740 E A I K I F N S L Q Q L E S M
Cat Felis silvestris
Mouse Mus musculus P97479 2215 254831 P1724 F S Y D Y F R P P P K H T L S
Rat Rattus norvegicus P70569 1846 213702 E1403 E I S R L T N E N L D F K E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510817 2096 240884 S1610 E A I K I F N S L Q Q L E S M
Chicken Gallus gallus Q02440 1829 212364 N1386 I T R L T N E N L D L M E Q L
Frog Xenopus laevis NP_001086419 2053 235941 S1566 E A V R I F N S L Q E I E T V
Zebra Danio Brachydanio rerio XP_698280 2068 236949 V1584 E A L K L F N V L H Q L E T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3Z6 2167 250290 L1711 D P I K A P L L R K L Q S K E
Honey Bee Apis mellifera XP_001122406 2102 243763 P1611 A I D H F R T P P K R T M S K
Nematode Worm Caenorhab. elegans P91443 2098 239766 F1559 S K N T L Q I F P K D M D L S
Sea Urchin Strong. purpuratus XP_781905 1686 195058 C1243 K T H K E E G C W K I T L H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 S1131 D L N L K S R S T P S S G N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 25.7 80.3 N.A. 27 25.1 N.A. 89.2 25 62.3 67.1 N.A. 25.1 25.7 24.9 44.1
Protein Similarity: 100 89.8 44 85.1 N.A. 44.5 46.4 N.A. 94.6 44.5 78.8 81.5 N.A. 45.1 46 45.4 60.1
P-Site Identity: 100 100 0 100 N.A. 6.6 13.3 N.A. 100 13.3 60 60 N.A. 13.3 6.6 0 6.6
P-Site Similarity: 100 100 26.6 100 N.A. 20 40 N.A. 100 33.3 100 80 N.A. 26.6 20 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 40 0 0 7 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 7 0 0 7 0 0 0 0 % C
% Asp: 14 0 7 7 0 0 0 0 0 7 14 0 7 0 0 % D
% Glu: 47 0 0 0 7 7 7 7 0 0 7 0 47 14 14 % E
% Phe: 7 0 0 0 7 47 0 7 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 7 0 0 14 0 0 % G
% His: 0 0 7 7 0 0 0 0 0 7 0 7 0 7 0 % H
% Ile: 7 14 34 0 34 0 7 0 0 0 7 7 0 0 0 % I
% Lys: 7 7 0 47 7 0 0 0 0 27 7 0 7 7 7 % K
% Leu: 0 7 7 14 27 0 14 7 47 7 14 34 7 14 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 14 7 0 27 % M
% Asn: 0 0 14 0 0 7 47 7 7 0 0 0 0 7 7 % N
% Pro: 0 7 0 0 0 14 0 20 20 14 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 34 34 14 0 7 0 % Q
% Arg: 7 0 7 20 0 7 14 0 7 0 7 0 0 0 0 % R
% Ser: 7 14 7 0 0 7 0 40 7 0 7 7 7 34 20 % S
% Thr: 0 14 0 7 7 7 7 0 7 0 0 14 7 14 0 % T
% Val: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _