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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HRASLS All Species: 16.97
Human Site: S141 Identified Species: 53.33
UniProt: Q9HDD0 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HDD0 NP_065119.1 168 18750 S141 E Q A N R A I S T V E F V T A
Chimpanzee Pan troglodytes XP_516953 273 30019 S246 E Q A N R A I S T V E F V T A
Rhesus Macaque Macaca mulatta XP_001095339 168 18788 S141 Q Q A N R A I S T V G F V T A
Dog Lupus familis XP_535846 169 18921 S142 E Q A N Q A I S T I G F M T A
Cat Felis silvestris
Mouse Mus musculus Q9QZU4 167 18791 G141 E Q A N R A I G T I G L V A A
Rat Rattus norvegicus P53817 160 17730 V134 Q V R D A V K V A T V T G V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513952 195 21984 V168 D Q V R D A L V G A S V A G V
Chicken Gallus gallus XP_422714 169 18744 S142 E Q A N R A I S A I G F V T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.5 96.4 84 N.A. 83.9 44 N.A. 38.9 72.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 61.5 97 89.9 N.A. 89.8 60.7 N.A. 52.3 84 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 66.6 0 N.A. 13.3 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 73.3 13.3 N.A. 26.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 75 0 13 88 0 0 25 13 0 0 13 13 75 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 13 13 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 63 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 13 0 50 0 13 13 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 75 0 0 38 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 13 0 0 0 0 13 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 25 88 0 0 13 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 13 13 63 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 63 0 0 13 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 63 13 0 13 0 63 0 % T
% Val: 0 13 13 0 0 13 0 25 0 38 13 13 63 13 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _