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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR6 All Species: 19.7
Human Site: S1002 Identified Species: 43.33
UniProt: Q9NNW5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NNW5 NP_060501.3 1121 121725 S1002 H H L V A S G S E D G S L H V
Chimpanzee Pan troglodytes XP_516448 1039 112101 S920 H H L V A S G S E D G S L H V
Rhesus Macaque Macaca mulatta XP_001111557 1121 121526 S1002 H H L V A S G S E D G S L H V
Dog Lupus familis XP_851202 1119 121377 E1002 H L V A S G S E D G S L H V F
Cat Felis silvestris
Mouse Mus musculus Q99ME2 1125 121879 S1006 H H L V A S G S E D G S L H V
Rat Rattus norvegicus Q5XFW6 1125 121918 S1006 H H L V A S G S E D G S L H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505572 1134 123896 D1008 Y L M A S G S D D G S I Q V C
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001107126 1193 129782 D1053 S L A S G G D D G Q L S L L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301542 1455 162451 S1350 N L F T S S E S M K N N C C R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192095 1308 144731 D1185 F N V I S G G D D Q A L H C L
Baker's Yeast Sacchar. cerevisiae Q08924 1013 114443 L910 T G G D D N G L G L S N L K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.5 97.6 93.4 N.A. 86.4 88.4 N.A. 49.2 N.A. N.A. 33 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.4 98.3 95.7 N.A. 92.6 93.3 N.A. 65.3 N.A. N.A. 50.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 0 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 21.3 N.A. N.A. 23 21.6 N.A.
Protein Similarity: 37.8 N.A. N.A. 39.9 39.3 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 33.3 N.A. N.A. 46.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 19 46 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 19 10 % C
% Asp: 0 0 0 10 10 0 10 28 28 46 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 46 0 0 0 0 0 0 % E
% Phe: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 10 0 10 37 64 0 19 19 46 0 0 0 0 % G
% His: 55 46 0 0 0 0 0 0 0 0 0 0 19 46 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % K
% Leu: 0 37 46 0 0 0 0 10 0 10 10 19 64 10 19 % L
% Met: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 10 0 0 0 0 10 19 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 19 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % R
% Ser: 10 0 0 10 37 55 19 55 0 0 28 55 0 0 0 % S
% Thr: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 19 46 0 0 0 0 0 0 0 0 0 19 46 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _