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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR6
All Species:
27.27
Human Site:
S228
Identified Species:
60
UniProt:
Q9NNW5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW5
NP_060501.3
1121
121725
S228
K
G
L
L
A
T
A
S
E
D
R
S
V
R
I
Chimpanzee
Pan troglodytes
XP_516448
1039
112101
H203
C
V
C
L
V
W
S
H
E
G
E
I
L
Q
A
Rhesus Macaque
Macaca mulatta
XP_001111557
1121
121526
S228
K
G
L
L
A
T
A
S
E
D
R
S
V
R
I
Dog
Lupus familis
XP_851202
1119
121377
S228
K
G
L
L
A
T
A
S
E
D
R
S
V
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99ME2
1125
121879
S228
K
G
L
L
A
T
A
S
E
D
R
S
V
R
L
Rat
Rattus norvegicus
Q5XFW6
1125
121918
S228
K
G
L
L
A
T
A
S
E
D
R
S
V
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505572
1134
123896
S239
K
G
I
L
A
S
A
S
D
D
R
S
I
R
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107126
1193
129782
S237
S
G
W
L
A
S
A
S
D
D
R
S
V
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301542
1455
162451
S252
L
R
F
Q
Q
H
K
S
A
H
M
C
R
L
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192095
1308
144731
K249
V
W
S
L
D
G
S
K
I
V
S
V
S
D
D
Baker's Yeast
Sacchar. cerevisiae
Q08924
1013
114443
R204
C
S
D
D
R
S
I
R
L
W
D
L
E
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
97.6
93.4
N.A.
86.4
88.4
N.A.
49.2
N.A.
N.A.
33
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.4
98.3
95.7
N.A.
92.6
93.3
N.A.
65.3
N.A.
N.A.
50.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
66.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
21.3
N.A.
N.A.
23
21.6
N.A.
Protein Similarity:
37.8
N.A.
N.A.
39.9
39.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
64
0
64
0
10
0
0
0
0
0
10
% A
% Cys:
19
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
10
10
0
0
0
19
64
10
0
0
10
10
% D
% Glu:
0
0
0
0
0
0
0
0
55
0
10
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
64
0
0
0
10
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
10
0
0
10
10
0
46
% I
% Lys:
55
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
46
82
0
0
0
0
10
0
0
10
10
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
0
0
10
0
0
10
0
0
64
0
10
64
0
% R
% Ser:
10
10
10
0
0
28
19
73
0
0
10
64
10
0
0
% S
% Thr:
0
0
0
0
0
46
0
0
0
0
0
0
0
10
0
% T
% Val:
10
10
0
0
10
0
0
0
0
10
0
10
55
0
10
% V
% Trp:
0
10
10
0
0
10
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _