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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR6 All Species: 31.82
Human Site: S934 Identified Species: 70
UniProt: Q9NNW5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NNW5 NP_060501.3 1121 121725 S934 R R R L L L C S A A T D G S L
Chimpanzee Pan troglodytes XP_516448 1039 112101 S852 R R R L L L C S A A T D G S L
Rhesus Macaque Macaca mulatta XP_001111557 1121 121526 S934 R R R L L L C S A A T D G N L
Dog Lupus familis XP_851202 1119 121377 S934 R R R L F L C S A A T D G S L
Cat Felis silvestris
Mouse Mus musculus Q99ME2 1125 121879 S938 R R R L I L C S A A T D G S L
Rat Rattus norvegicus Q5XFW6 1125 121918 S938 R R R L I L C S A A T D G S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505572 1134 123896 S940 E R R V L L C S A V T D G S I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001107126 1193 129782 S985 R K L L L L F S A T T D G C I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301542 1455 162451 V1282 P F H V F N N V H Q S G V N S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192095 1308 144731 S1117 A A E E D P A S S L E L T N D
Baker's Yeast Sacchar. cerevisiae Q08924 1013 114443 Y842 T D G H L V V Y N I T E Y V P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.5 97.6 93.4 N.A. 86.4 88.4 N.A. 49.2 N.A. N.A. 33 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.4 98.3 95.7 N.A. 92.6 93.3 N.A. 65.3 N.A. N.A. 50.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 86.6 N.A. 73.3 N.A. N.A. 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 86.6 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 21.3 N.A. N.A. 23 21.6 N.A.
Protein Similarity: 37.8 N.A. N.A. 39.9 39.3 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 20 N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 10 0 73 55 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 64 0 0 0 0 0 0 10 0 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 73 0 0 10 % D
% Glu: 10 0 10 10 0 0 0 0 0 0 10 10 0 0 0 % E
% Phe: 0 10 0 0 19 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 10 73 0 0 % G
% His: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 19 0 0 0 0 10 0 0 0 0 28 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 64 55 73 0 0 0 10 0 10 0 0 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 10 0 10 0 0 0 0 28 0 % N
% Pro: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 64 64 64 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 82 10 0 10 0 0 55 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 10 82 0 10 0 0 % T
% Val: 0 0 0 19 0 10 10 10 0 10 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _