KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR6
All Species:
25.15
Human Site:
T585
Identified Species:
55.33
UniProt:
Q9NNW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW5
NP_060501.3
1121
121725
T585
H
G
G
Y
V
Y
T
T
G
R
D
G
A
Y
Y
Chimpanzee
Pan troglodytes
XP_516448
1039
112101
T503
H
G
G
F
V
Y
T
T
G
R
D
G
A
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001111557
1121
121526
T585
H
G
G
Y
V
Y
T
T
G
R
D
G
A
Y
Y
Dog
Lupus familis
XP_851202
1119
121377
T585
H
G
G
Y
V
Y
T
T
G
R
D
G
A
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99ME2
1125
121879
T585
H
G
G
Y
L
Y
S
T
G
R
D
S
S
Y
F
Rat
Rattus norvegicus
Q5XFW6
1125
121918
T585
H
G
G
Y
V
Y
S
T
G
R
D
G
S
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505572
1134
123896
G593
F
G
V
H
G
K
Q
G
V
T
S
V
T
C
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107126
1193
129782
T616
Y
Q
D
L
C
Y
S
T
G
R
D
G
S
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301542
1455
162451
L748
K
Q
V
K
E
L
S
L
V
Q
S
V
S
A
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192095
1308
144731
E635
D
G
C
I
C
Y
F
E
Y
D
R
E
M
Q
T
Baker's Yeast
Sacchar. cerevisiae
Q08924
1013
114443
I506
E
S
E
E
P
F
I
I
R
R
L
S
P
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
97.6
93.4
N.A.
86.4
88.4
N.A.
49.2
N.A.
N.A.
33
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.4
98.3
95.7
N.A.
92.6
93.3
N.A.
65.3
N.A.
N.A.
50.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
66.6
86.6
N.A.
6.6
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
20
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
21.3
N.A.
N.A.
23
21.6
N.A.
Protein Similarity:
37.8
N.A.
N.A.
39.9
39.3
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
37
10
0
% A
% Cys:
0
0
10
0
19
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
10
64
0
0
0
19
% D
% Glu:
10
0
10
10
10
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
10
0
0
10
0
10
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
73
55
0
10
0
0
10
64
0
0
55
0
10
0
% G
% His:
55
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
10
0
10
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
19
0
0
0
0
10
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
73
10
0
0
0
10
% R
% Ser:
0
10
0
0
0
0
37
0
0
0
19
19
37
0
0
% S
% Thr:
0
0
0
0
0
0
37
64
0
10
0
0
10
0
10
% T
% Val:
0
0
19
0
46
0
0
0
19
0
0
19
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
46
0
73
0
0
10
0
0
0
0
55
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _