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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR6
All Species:
20.91
Human Site:
Y591
Identified Species:
46
UniProt:
Q9NNW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW5
NP_060501.3
1121
121725
Y591
T
T
G
R
D
G
A
Y
Y
Q
L
F
V
R
D
Chimpanzee
Pan troglodytes
XP_516448
1039
112101
Y509
T
T
G
R
D
G
A
Y
Y
Q
L
F
V
R
D
Rhesus Macaque
Macaca mulatta
XP_001111557
1121
121526
Y591
T
T
G
R
D
G
A
Y
Y
Q
L
F
V
R
D
Dog
Lupus familis
XP_851202
1119
121377
Y591
T
T
G
R
D
G
A
Y
Y
Q
L
F
V
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99ME2
1125
121879
Y591
S
T
G
R
D
S
S
Y
F
Q
L
F
V
H
G
Rat
Rattus norvegicus
Q5XFW6
1125
121918
Y591
S
T
G
R
D
G
S
Y
Y
Q
L
F
V
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505572
1134
123896
C599
Q
G
V
T
S
V
T
C
H
G
G
F
I
Y
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107126
1193
129782
V622
S
T
G
R
D
G
S
V
R
I
L
T
V
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301542
1455
162451
A754
S
L
V
Q
S
V
S
A
D
N
N
C
L
D
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192095
1308
144731
Q641
F
E
Y
D
R
E
M
Q
T
L
E
F
M
G
L
Baker's Yeast
Sacchar. cerevisiae
Q08924
1013
114443
G512
I
I
R
R
L
S
P
G
D
T
T
T
S
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
97.6
93.4
N.A.
86.4
88.4
N.A.
49.2
N.A.
N.A.
33
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.4
98.3
95.7
N.A.
92.6
93.3
N.A.
65.3
N.A.
N.A.
50.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
60
73.3
N.A.
6.6
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
20
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
21.3
N.A.
N.A.
23
21.6
N.A.
Protein Similarity:
37.8
N.A.
N.A.
39.9
39.3
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
37
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
64
0
0
0
19
0
0
0
0
10
37
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
10
0
0
10
19
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
73
0
0
0
% F
% Gly:
0
10
64
0
0
55
0
10
0
10
10
0
0
10
28
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
19
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
10
64
0
10
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
10
0
55
0
0
0
0
0
% Q
% Arg:
0
0
10
73
10
0
0
0
10
0
0
0
0
37
0
% R
% Ser:
37
0
0
0
19
19
37
0
0
0
0
0
10
0
10
% S
% Thr:
37
64
0
10
0
0
10
0
10
10
10
19
0
0
0
% T
% Val:
0
0
19
0
0
19
0
10
0
0
0
0
64
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
55
46
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _