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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
23.94
Human Site:
S282
Identified Species:
35.11
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
S282
F
L
R
G
C
A
P
S
R
V
R
R
L
P
D
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
L252
I
M
M
R
S
I
P
L
R
G
F
D
Q
Q
M
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
S282
F
L
R
G
C
A
P
S
R
V
R
R
L
P
D
Dog
Lupus familis
XP_850181
509
55065
S269
F
L
R
G
C
T
P
S
R
V
R
R
L
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
S282
F
L
K
G
C
V
P
S
H
I
K
K
L
P
T
Rat
Rattus norvegicus
Q9Z0J5
526
56406
S284
F
L
K
G
C
V
P
S
L
I
R
K
L
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
A276
F
L
K
K
C
V
P
A
K
V
E
K
L
E
S
Frog
Xenopus laevis
NP_001080052
504
54666
S262
F
L
W
K
C
T
P
S
H
V
E
K
L
K
N
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
T357
F
L
R
K
F
V
P
T
K
I
E
Q
L
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
L356
F
L
R
K
T
V
P
L
S
V
E
K
Q
D
D
Honey Bee
Apis mellifera
NP_001171496
537
59227
S297
F
I
Y
E
A
K
P
S
K
I
E
K
Q
A
D
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
R415
F
E
A
G
V
P
T
R
I
E
Q
I
D
E
K
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
E253
F
L
W
Q
Q
V
P
E
S
V
A
K
N
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
N260
N
L
E
G
R
G
V
N
L
H
P
Q
T
S
L
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
N242
K
F
D
E
C
I
Q
N
T
I
T
D
H
Y
V
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
L241
K
V
H
K
K
S
Q
L
T
S
V
Q
K
D
A
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
13.3
100
93.3
N.A.
53.3
60
N.A.
N.A.
40
46.6
33.3
N.A.
40
26.6
13.3
26.6
P-Site Similarity:
100
20
100
93.3
N.A.
80
80
N.A.
N.A.
66.6
60
60
N.A.
46.6
53.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
13
0
7
0
0
7
0
0
7
13
% A
% Cys:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
13
7
13
32
% D
% Glu:
0
7
7
13
0
0
0
7
0
7
32
0
0
19
0
% E
% Phe:
75
7
0
0
7
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
44
0
7
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
13
7
0
0
7
0
0
% H
% Ile:
7
7
0
0
0
13
0
0
7
32
0
7
0
0
0
% I
% Lys:
13
0
19
32
7
7
0
0
19
0
7
44
7
7
7
% K
% Leu:
0
69
0
0
0
0
0
19
13
0
0
0
50
0
7
% L
% Met:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
0
0
0
0
13
0
0
0
0
7
0
13
% N
% Pro:
0
0
0
0
0
7
75
0
0
0
7
0
0
32
0
% P
% Gln:
0
0
0
7
7
0
13
0
0
0
7
19
19
13
0
% Q
% Arg:
0
0
32
7
7
0
0
7
25
0
25
19
0
0
0
% R
% Ser:
0
0
0
0
7
7
0
44
13
7
0
0
0
7
7
% S
% Thr:
0
0
0
0
7
13
7
7
13
0
7
0
7
0
13
% T
% Val:
0
7
0
0
7
38
7
0
0
44
7
0
0
0
7
% V
% Trp:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _