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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
30.91
Human Site:
S513
Identified Species:
45.33
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
S513
K
L
R
I
S
K
R
S
G
L
D
P
T
V
T
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
E471
F
L
G
P
N
A
G
E
V
T
Q
G
F
A
L
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
S513
K
L
R
I
S
K
R
S
G
L
D
P
T
V
T
Dog
Lupus familis
XP_850181
509
55065
A492
P
T
C
A
E
E
V
A
K
L
R
I
T
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
S513
K
L
H
I
S
K
R
S
G
L
E
P
T
V
T
Rat
Rattus norvegicus
Q9Z0J5
526
56406
S515
K
L
H
I
S
K
R
S
G
L
D
P
T
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
S507
K
L
H
I
T
K
R
S
G
L
D
A
T
V
T
Frog
Xenopus laevis
NP_001080052
504
54666
S493
K
L
H
I
T
K
R
S
G
L
D
P
T
V
T
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
S591
T
M
E
V
T
K
S
S
G
G
D
I
T
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
S585
R
L
A
I
T
K
R
S
G
L
D
P
T
P
A
Honey Bee
Apis mellifera
NP_001171496
537
59227
S526
R
I
S
V
T
K
R
S
G
L
D
P
K
P
Q
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
E655
T
L
T
L
E
K
K
E
G
D
E
E
L
Q
A
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
V473
P
T
C
A
E
E
V
V
K
I
H
I
T
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
R488
T
M
R
S
V
T
R
R
I
A
H
K
P
K
P
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
N467
A
T
K
A
D
F
D
N
C
V
A
I
H
P
T
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
P458
D
N
C
V
A
I
H
P
T
S
A
E
E
L
V
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
6.6
100
13.3
N.A.
86.6
93.3
N.A.
N.A.
80
86.6
33.3
N.A.
66.6
46.6
20
6.6
P-Site Similarity:
100
13.3
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
93.3
60
N.A.
80
73.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
19
7
7
0
7
0
7
13
7
0
7
13
% A
% Cys:
0
0
19
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
7
0
0
7
50
0
0
0
0
% D
% Glu:
0
0
7
0
19
13
0
13
0
0
13
13
7
0
0
% E
% Phe:
7
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
0
7
0
63
7
0
7
0
0
0
% G
% His:
0
0
25
0
0
0
7
0
0
0
13
0
7
0
0
% H
% Ile:
0
7
0
44
0
7
0
0
7
7
0
25
0
0
0
% I
% Lys:
38
0
7
0
0
63
7
0
13
0
0
7
7
19
0
% K
% Leu:
0
57
0
7
0
0
0
0
0
57
0
0
7
7
7
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
7
0
0
0
7
0
0
0
44
7
19
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
13
7
% Q
% Arg:
13
0
19
0
0
0
57
7
0
0
7
0
0
0
13
% R
% Ser:
0
0
7
7
25
0
7
57
0
7
0
0
0
0
7
% S
% Thr:
19
19
7
0
32
7
0
0
7
7
0
0
63
0
44
% T
% Val:
0
0
0
19
7
0
13
7
7
7
0
0
0
38
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _