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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
23.03
Human Site:
T295
Identified Species:
33.78
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
T295
P
D
G
Q
L
Q
V
T
W
E
D
S
T
T
G
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
E265
Q
M
S
S
M
V
I
E
H
M
A
S
H
G
T
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
T295
P
D
G
H
L
Q
V
T
W
E
D
C
T
T
G
Dog
Lupus familis
XP_850181
509
55065
T282
P
D
G
Q
L
Q
V
T
W
E
N
L
T
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
T295
P
T
N
Q
L
Q
V
T
W
E
D
H
A
S
G
Rat
Rattus norvegicus
Q9Z0J5
526
56406
T297
P
T
N
Q
L
Q
V
T
W
E
D
L
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
T289
E
S
S
R
L
Q
V
T
W
K
N
T
E
L
G
Frog
Xenopus laevis
NP_001080052
504
54666
T275
K
N
G
K
L
Q
V
T
W
K
N
T
Q
S
G
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
I370
E
A
G
T
P
G
R
I
K
V
T
A
K
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
K369
D
D
G
K
L
L
V
K
Y
K
N
V
E
T
G
Honey Bee
Apis mellifera
NP_001171496
537
59227
H310
A
D
G
R
L
L
V
H
W
V
D
K
D
R
Q
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
G428
E
K
T
D
E
K
A
G
K
Y
R
V
F
W
P
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
R266
Q
N
G
S
L
N
V
R
W
R
S
D
Q
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
T273
S
L
T
Q
L
T
K
T
D
Q
G
I
K
V
I
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
V255
Y
V
K
E
G
I
N
V
H
K
L
S
K
I
V
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
I254
D
A
A
G
K
L
A
I
N
F
K
E
G
E
G
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
6.6
86.6
80
N.A.
66.6
66.6
N.A.
N.A.
40
46.6
6.6
N.A.
40
40
0
26.6
P-Site Similarity:
100
20
86.6
93.3
N.A.
73.3
73.3
N.A.
N.A.
66.6
86.6
20
N.A.
66.6
46.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
7
0
0
0
13
0
0
0
7
7
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
13
32
0
7
0
0
0
0
7
0
32
7
7
0
0
% D
% Glu:
19
0
0
7
7
0
0
7
0
32
0
7
13
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% F
% Gly:
0
0
50
7
7
7
0
7
0
0
7
0
7
13
57
% G
% His:
0
0
0
7
0
0
0
7
13
0
0
7
7
0
0
% H
% Ile:
0
0
0
0
0
7
7
13
0
0
0
7
0
7
7
% I
% Lys:
7
7
7
13
7
7
7
7
13
25
7
7
19
0
0
% K
% Leu:
0
7
0
0
69
19
0
0
0
0
7
13
0
7
0
% L
% Met:
0
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
13
13
0
0
7
7
0
7
0
25
0
0
0
0
% N
% Pro:
32
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
13
0
0
32
0
44
0
0
0
7
0
0
13
0
13
% Q
% Arg:
0
0
0
13
0
0
7
7
0
7
7
0
0
7
0
% R
% Ser:
7
7
13
13
0
0
0
0
0
0
7
19
0
32
0
% S
% Thr:
0
13
13
7
0
7
0
50
0
0
7
13
19
19
13
% T
% Val:
0
7
0
0
0
7
63
7
0
13
0
13
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
57
0
0
0
0
7
0
% W
% Tyr:
7
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _