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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUFT1 All Species: 3.94
Human Site: S131 Identified Species: 12.38
UniProt: Q9NNX1 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NNX1 NP_001119809.1 390 44264 S131 L D R N L G D S L H R Q E I Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540317 360 40806 D131 Y S S P P E V D G Y I N E D V
Cat Felis silvestris
Mouse Mus musculus O08970 390 44558 P131 L D R S P G D P L R Q Q E I Q
Rat Rattus norvegicus Q5EB94 466 53937 S186 V D V T L E N S N I K D Q I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234135 373 42726 E144 R L R A E P W E E Q D E D C S
Frog Xenopus laevis Q5U4W1 666 76282 A373 M K Q A A Q K A Q R L Q Q V L
Zebra Danio Brachydanio rerio NP_001073470 384 45202 S142 R K V N G T H S A L T Q S L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S304 707 80536 V305 E D Y A R T D V F K Q F K A Q
Conservation
Percent
Protein Identity: 100 N.A. N.A. 78.4 N.A. 88.9 21.6 N.A. N.A. 53.3 20.7 33.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 83.5 N.A. 93.5 42.9 N.A. N.A. 68.9 35.8 54.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 66.6 26.6 N.A. N.A. 6.6 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 80 60 N.A. N.A. 20 40 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 38 13 0 0 13 13 0 0 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % C
% Asp: 0 50 0 0 0 0 38 13 0 0 13 13 13 13 0 % D
% Glu: 13 0 0 0 13 25 0 13 13 0 0 13 38 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 13 0 0 13 0 0 0 % F
% Gly: 0 0 0 0 13 25 0 0 13 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 13 0 0 13 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 13 13 0 0 38 0 % I
% Lys: 0 25 0 0 0 0 13 0 0 13 13 0 13 0 0 % K
% Leu: 25 13 0 0 25 0 0 0 25 13 13 0 0 13 13 % L
% Met: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 25 0 0 13 0 13 0 0 13 0 0 13 % N
% Pro: 0 0 0 13 25 13 0 13 0 0 0 0 0 0 0 % P
% Gln: 0 0 13 0 0 13 0 0 13 13 25 50 25 0 38 % Q
% Arg: 25 0 38 0 13 0 0 0 0 25 13 0 0 0 13 % R
% Ser: 0 13 13 13 0 0 0 38 0 0 0 0 13 0 13 % S
% Thr: 0 0 0 13 0 25 0 0 0 0 13 0 0 0 0 % T
% Val: 13 0 25 0 0 0 13 13 0 0 0 0 0 13 13 % V
% Trp: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 13 0 0 0 0 0 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _