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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE7B
All Species:
4.55
Human Site:
S449
Identified Species:
11.11
UniProt:
Q9NP56
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP56
NP_061818.1
450
51835
S449
S
E
E
Q
E
G
D
S
P
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001157383
650
72760
S649
S
E
E
Q
E
G
D
S
P
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001100632
505
57975
E501
S
E
E
Q
T
A
R
E
G
D
S
P
_
_
_
Dog
Lupus familis
XP_541113
505
57737
I501
N
E
E
Q
T
G
T
I
G
D
A
P
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXQ1
446
51318
P435
Q
D
L
A
G
P
A
P
E
T
L
E
Q
T
E
Rat
Rattus norvegicus
O08593
426
49255
Q417
A
A
F
E
L
N
S
Q
L
L
T
Q
E
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511626
509
58136
Q501
P
V
T
E
N
E
E
Q
T
F
T
E
G
E
T
Chicken
Gallus gallus
XP_419729
443
51284
E439
S
Q
E
Q
T
L
N
E
E
E
T
P
_
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923883
490
55552
E489
A
L
T
Q
G
S
P
E
S
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22000
674
75370
A664
I
P
E
E
P
D
T
A
R
T
V
T
E
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.3
84.5
79.5
N.A.
91.3
57.3
N.A.
75.2
83.5
N.A.
55.9
N.A.
N.A.
N.A.
24.4
N.A.
Protein Similarity:
100
68.7
86.1
82.7
N.A.
94.2
72.8
N.A.
80.9
90.4
N.A.
69.1
N.A.
N.A.
N.A.
40
N.A.
P-Site Identity:
100
100
33.3
33.3
N.A.
0
0
N.A.
0
25
N.A.
11.1
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
41.6
N.A.
6.6
13.3
N.A.
20
41.6
N.A.
22.2
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
10
0
10
10
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
20
0
0
20
0
0
0
10
10
% D
% Glu:
0
40
60
30
20
10
10
30
20
10
0
20
20
10
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
20
30
0
0
20
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
10
10
0
0
10
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
10
10
0
0
0
0
0
0
10
0
% N
% Pro:
10
10
0
0
10
10
10
10
20
0
0
30
0
0
0
% P
% Gln:
10
10
0
60
0
0
0
20
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% R
% Ser:
40
0
0
0
0
10
10
20
10
0
10
0
0
0
0
% S
% Thr:
0
0
20
0
30
0
20
0
10
20
30
10
0
10
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
30
30
30
60
60
60
% _