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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB6
All Species:
26.67
Human Site:
S378
Identified Species:
48.89
UniProt:
Q9NP58
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP58
NP_005680.1
842
93886
S378
R
I
A
D
R
G
T
S
S
V
T
G
L
L
S
Chimpanzee
Pan troglodytes
XP_001161097
843
94009
S378
R
I
A
D
R
G
T
S
S
V
T
G
L
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536073
1099
120564
S637
R
I
V
D
R
G
T
S
S
V
T
G
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC29
842
93752
S378
R
I
V
D
R
G
T
S
S
V
T
G
L
L
S
Rat
Rattus norvegicus
O70595
836
93286
S378
R
I
V
D
R
G
T
S
S
V
T
G
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139165
800
90747
S370
R
S
I
D
R
G
T
S
S
I
N
S
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650503
866
97867
D363
R
V
M
D
R
G
T
D
S
I
N
N
L
L
N
Honey Bee
Apis mellifera
XP_001122583
748
85114
T320
F
G
L
I
V
F
L
T
M
S
L
Y
I
A
A
Nematode Worm
Caenorhab. elegans
NP_001022812
801
90557
V351
N
Y
I
L
F
N
V
V
P
T
I
A
D
I
V
Sea Urchin
Strong. purpuratus
XP_001181861
832
94582
T364
R
M
M
D
R
G
T
T
S
I
N
S
L
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
A300
I
L
A
Y
K
F
G
A
A
F
A
W
I
T
S
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
T262
G
A
S
F
A
A
I
T
F
S
T
M
L
L
Y
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
L288
S
Y
T
A
F
T
I
L
T
T
A
W
R
T
K
Conservation
Percent
Protein Identity:
100
99.5
N.A.
67.7
N.A.
88.9
87.4
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
49.5
50
42.5
51.3
Protein Similarity:
100
99.6
N.A.
71.5
N.A.
93.4
92.9
N.A.
N.A.
N.A.
N.A.
74.9
N.A.
64.7
65.9
59.1
66.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
53.3
0
0
60
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
73.3
20
6.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
33
35.2
Protein Similarity:
N.A.
N.A.
N.A.
52.4
49.5
51.5
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
8
8
8
0
8
8
0
16
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
16
16
0
0
8
8
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
62
8
0
0
0
0
39
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
39
16
8
0
0
16
0
0
24
8
0
16
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
8
8
0
0
8
8
0
0
8
0
70
70
0
% L
% Met:
0
8
16
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
24
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
62
0
0
0
62
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
8
8
0
0
0
0
47
62
16
0
16
0
0
62
% S
% Thr:
0
0
8
0
0
8
62
24
8
16
47
0
0
16
0
% T
% Val:
0
8
24
0
8
0
8
8
0
39
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% W
% Tyr:
0
16
0
8
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _