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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB6
All Species:
21.52
Human Site:
S655
Identified Species:
39.44
UniProt:
Q9NP58
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP58
NP_005680.1
842
93886
S655
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
Chimpanzee
Pan troglodytes
XP_001161097
843
94009
S655
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536073
1099
120564
S914
R
I
D
G
Q
D
I
S
Q
V
T
Q
I
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC29
842
93752
S655
R
I
D
G
Q
D
I
S
Q
V
T
Q
I
S
L
Rat
Rattus norvegicus
O70595
836
93286
S655
R
I
D
G
Q
D
I
S
Q
V
T
Q
I
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139165
800
90747
Q635
L
F
R
F
Y
D
V
Q
G
G
C
I
K
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650503
866
97867
K641
L
I
D
G
Q
N
I
K
L
V
Q
Q
Q
S
L
Honey Bee
Apis mellifera
XP_001122583
748
85114
N584
F
N
N
T
I
K
Y
N
I
Q
Y
G
R
I
E
Nematode Worm
Caenorhab. elegans
NP_001022812
801
90557
R615
E
F
D
G
I
D
V
R
N
Y
T
M
H
S
L
Sea Urchin
Strong. purpuratus
XP_001181861
832
94582
S642
R
L
D
G
Q
D
I
S
K
V
A
Q
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
L564
V
V
P
Q
D
T
V
L
F
N
D
T
I
F
H
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
I526
T
P
L
F
N
D
T
I
W
E
N
V
K
F
G
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
P552
Y
G
N
L
S
A
T
P
E
Q
V
I
E
A
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
67.7
N.A.
88.9
87.4
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
49.5
50
42.5
51.3
Protein Similarity:
100
99.6
N.A.
71.5
N.A.
93.4
92.9
N.A.
N.A.
N.A.
N.A.
74.9
N.A.
64.7
65.9
59.1
66.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
60
0
40
73.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
66.6
13.3
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
33
35.2
Protein Similarity:
N.A.
N.A.
N.A.
52.4
49.5
51.5
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
8
0
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
62
0
8
70
0
0
0
0
8
0
0
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
8
8
0
0
8
0
8
% E
% Phe:
8
16
0
16
0
0
0
0
8
0
0
0
0
16
0
% F
% Gly:
0
8
0
62
0
0
0
0
8
8
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
47
0
0
16
0
54
8
8
0
0
16
31
16
0
% I
% Lys:
0
0
0
0
0
8
0
8
8
0
0
0
16
0
0
% K
% Leu:
16
8
8
8
0
0
0
8
8
0
0
0
0
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
16
0
8
8
0
8
8
8
8
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
54
0
0
8
39
16
8
54
8
0
0
% Q
% Arg:
47
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
8
0
0
47
0
0
0
0
8
62
0
% S
% Thr:
8
0
0
8
0
8
16
0
0
0
47
8
0
0
0
% T
% Val:
8
8
0
0
0
0
24
0
0
54
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
8
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _