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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB6 All Species: 9.09
Human Site: S813 Identified Species: 16.67
UniProt: Q9NP58 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP58 NP_005680.1 842 93886 S813 G R H E A L L S R G G V Y A D
Chimpanzee Pan troglodytes XP_001161097 843 94009 S813 G R H E A L L S R G G V Y A D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536073 1099 120564 E1063 F K D G W I V E R G R H E A L
Cat Felis silvestris
Mouse Mus musculus Q9DC29 842 93752 S813 G R H E A L L S R G G V Y A E
Rat Rattus norvegicus O70595 836 93286 E804 I K D G C I I E R G R H E A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139165 800 90747 V772 C A N R T T V V V A H R L S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650503 866 97867 R800 R H E E L V L R E D G I Y A D
Honey Bee Apis mellifera XP_001122583 748 85114 H720 I S Y N G M Y H S M W Q A Q L
Nematode Worm Caenorhab. elegans NP_001022812 801 90557 A773 G N H K E L L A Q Q G T Y A S
Sea Urchin Strong. purpuratus XP_001181861 832 94582 G800 G R H E Q L L G L D G I Y A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVM1 728 80402 L700 E Q G P H D E L L G K S G R Y
Baker's Yeast Sacchar. cerevisiae P40416 690 77504 M662 K H L E L L A M P G S L Y R E
Red Bread Mold Neurospora crassa Q7RX59 716 78739 W688 N G V Y A Q L W R A Q E M L M
Conservation
Percent
Protein Identity: 100 99.5 N.A. 67.7 N.A. 88.9 87.4 N.A. N.A. N.A. N.A. 61.7 N.A. 49.5 50 42.5 51.3
Protein Similarity: 100 99.6 N.A. 71.5 N.A. 93.4 92.9 N.A. N.A. N.A. N.A. 74.9 N.A. 64.7 65.9 59.1 66.2
P-Site Identity: 100 100 N.A. 20 N.A. 93.3 20 N.A. N.A. N.A. N.A. 0 N.A. 40 0 46.6 66.6
P-Site Similarity: 100 100 N.A. 40 N.A. 100 40 N.A. N.A. N.A. N.A. 20 N.A. 53.3 13.3 66.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 36.3 33 35.2
Protein Similarity: N.A. N.A. N.A. 52.4 49.5 51.5
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 20
P-Site Similarity: N.A. N.A. N.A. 13.3 40 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 31 0 8 8 0 16 0 0 8 62 0 % A
% Cys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 0 8 0 0 0 16 0 0 0 0 31 % D
% Glu: 8 0 8 47 8 0 8 16 8 0 0 8 16 0 16 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 39 8 8 16 8 0 0 8 0 54 47 0 8 0 0 % G
% His: 0 16 39 0 8 0 0 8 0 0 8 16 0 0 0 % H
% Ile: 16 0 0 0 0 16 8 0 0 0 0 16 0 0 0 % I
% Lys: 8 16 0 8 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 8 0 16 47 54 8 16 0 0 8 8 8 24 % L
% Met: 0 0 0 0 0 8 0 8 0 8 0 0 8 0 8 % M
% Asn: 8 8 8 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 8 8 0 0 8 8 8 8 0 8 0 % Q
% Arg: 8 31 0 8 0 0 0 8 47 0 16 8 0 16 0 % R
% Ser: 0 8 0 0 0 0 0 24 8 0 8 8 0 8 8 % S
% Thr: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 8 % T
% Val: 0 0 8 0 0 8 16 8 8 0 0 24 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 8 0 0 0 0 0 54 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _