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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB6 All Species: 30.3
Human Site: T366 Identified Species: 55.56
UniProt: Q9NP58 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP58 NP_005680.1 842 93886 T366 R W H L G R R T G E V L R I A
Chimpanzee Pan troglodytes XP_001161097 843 94009 T366 R W H L G R R T G E V L R I A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536073 1099 120564 T625 R W H L G R R T G E V L R I V
Cat Felis silvestris
Mouse Mus musculus Q9DC29 842 93752 T366 R W H L G R R T G E V L R I V
Rat Rattus norvegicus O70595 836 93286 T366 R W H L G R R T G E V L R I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139165 800 90747 T358 R W H L G R R T G D V L R S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650503 866 97867 T351 R W H L Q R K T G E V L R V M
Honey Bee Apis mellifera XP_001122583 748 85114 A308 A V A F F I V A F N K W F G L
Nematode Worm Caenorhab. elegans NP_001022812 801 90557 V339 M D R G T S S V N N I L N Y I
Sea Urchin Strong. purpuratus XP_001181861 832 94582 T352 R W H L N R K T G E V L R M M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVM1 728 80402 S288 V P T I L E I S M V S G I L A
Baker's Yeast Sacchar. cerevisiae P40416 690 77504 L250 I S V V C G I L T Y Q F G A S
Red Bread Mold Neurospora crassa Q7RX59 716 78739 A276 W Q Y A A L T A L T M V S Y T
Conservation
Percent
Protein Identity: 100 99.5 N.A. 67.7 N.A. 88.9 87.4 N.A. N.A. N.A. N.A. 61.7 N.A. 49.5 50 42.5 51.3
Protein Similarity: 100 99.6 N.A. 71.5 N.A. 93.4 92.9 N.A. N.A. N.A. N.A. 74.9 N.A. 64.7 65.9 59.1 66.2
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 80 N.A. 73.3 0 6.6 73.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 86.6 N.A. 86.6 0 13.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 36.3 33 35.2
Protein Similarity: N.A. N.A. N.A. 52.4 49.5 51.5
P-Site Identity: N.A. N.A. N.A. 6.6 0 0
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 8 0 0 16 0 0 0 0 0 8 24 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 54 0 0 0 0 0 % E
% Phe: 0 0 0 8 8 0 0 0 8 0 0 8 8 0 0 % F
% Gly: 0 0 0 8 47 8 0 0 62 0 0 8 8 8 0 % G
% His: 0 0 62 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 8 0 8 16 0 0 0 8 0 8 39 16 % I
% Lys: 0 0 0 0 0 0 16 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 62 8 8 0 8 8 0 0 70 0 8 8 % L
% Met: 8 0 0 0 0 0 0 0 8 0 8 0 0 8 16 % M
% Asn: 0 0 0 0 8 0 0 0 8 16 0 0 8 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 8 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 62 0 8 0 0 62 47 0 0 0 0 0 62 0 0 % R
% Ser: 0 8 0 0 0 8 8 8 0 0 8 0 8 8 8 % S
% Thr: 0 0 8 0 8 0 8 62 8 8 0 0 0 0 8 % T
% Val: 8 8 8 8 0 0 8 8 0 8 62 8 0 8 24 % V
% Trp: 8 62 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 8 0 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _