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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB6
All Species:
20.3
Human Site:
T605
Identified Species:
37.22
UniProt:
Q9NP58
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP58
NP_005680.1
842
93886
T605
S
Y
A
D
G
R
E
T
L
Q
D
V
S
F
T
Chimpanzee
Pan troglodytes
XP_001161097
843
94009
T605
S
Y
A
D
G
R
E
T
L
Q
D
V
S
F
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536073
1099
120564
T864
S
Y
A
N
G
R
E
T
L
Q
D
V
S
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC29
842
93752
T605
S
Y
A
D
G
Q
E
T
L
Q
D
V
S
F
T
Rat
Rattus norvegicus
O70595
836
93286
T605
S
Y
A
D
G
R
E
T
L
Q
D
V
S
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139165
800
90747
E585
R
Q
G
K
V
E
F
E
N
V
F
F
S
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650503
866
97867
V591
G
Y
S
P
E
K
I
V
L
R
N
V
S
F
T
Honey Bee
Apis mellifera
XP_001122583
748
85114
V534
G
S
G
K
S
T
I
V
R
L
L
F
R
F
Y
Nematode Worm
Caenorhab. elegans
NP_001022812
801
90557
V565
E
Y
N
T
G
L
P
V
I
K
N
I
S
F
E
Sea Urchin
Strong. purpuratus
XP_001181861
832
94582
L592
Y
N
E
Q
K
P
I
L
R
N
V
S
F
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
S514
S
V
A
I
V
G
T
S
G
S
G
K
S
T
I
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
S476
G
S
S
G
S
G
K
S
T
I
L
K
L
V
F
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
Q502
L
F
R
F
Y
D
P
Q
K
G
A
I
Y
I
D
Conservation
Percent
Protein Identity:
100
99.5
N.A.
67.7
N.A.
88.9
87.4
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
49.5
50
42.5
51.3
Protein Similarity:
100
99.6
N.A.
71.5
N.A.
93.4
92.9
N.A.
N.A.
N.A.
N.A.
74.9
N.A.
64.7
65.9
59.1
66.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
40
6.6
26.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
20
N.A.
66.6
6.6
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
33
35.2
Protein Similarity:
N.A.
N.A.
N.A.
52.4
49.5
51.5
P-Site Identity:
N.A.
N.A.
N.A.
20
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
8
0
0
0
0
39
0
0
0
8
% D
% Glu:
8
0
8
0
8
8
39
8
0
0
0
0
0
0
8
% E
% Phe:
0
8
0
8
0
0
8
0
0
0
8
16
8
62
8
% F
% Gly:
24
0
16
8
47
16
0
0
8
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
24
0
8
8
0
16
0
8
8
% I
% Lys:
0
0
0
16
8
8
8
0
8
8
0
16
0
0
0
% K
% Leu:
8
0
0
0
0
8
0
8
47
8
16
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
0
0
8
8
16
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
16
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
8
0
8
0
39
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
31
0
0
16
8
0
0
8
0
0
% R
% Ser:
47
16
16
0
16
0
0
16
0
8
0
8
70
0
0
% S
% Thr:
0
0
0
8
0
8
8
39
8
0
0
0
0
16
54
% T
% Val:
0
8
0
0
16
0
0
24
0
8
8
47
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
54
0
0
8
0
0
0
0
0
0
0
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _