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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB6
All Species:
22.42
Human Site:
Y686
Identified Species:
41.11
UniProt:
Q9NP58
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP58
NP_005680.1
842
93886
Y686
T
I
A
D
N
I
R
Y
G
R
V
T
A
G
N
Chimpanzee
Pan troglodytes
XP_001161097
843
94009
Y686
T
I
A
D
N
I
R
Y
G
R
V
T
A
G
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536073
1099
120564
Y945
T
I
A
N
N
I
R
Y
G
C
I
T
A
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC29
842
93752
Y686
T
I
A
N
N
I
R
Y
G
R
V
T
A
G
D
Rat
Rattus norvegicus
O70595
836
93286
Y686
T
I
A
N
N
I
R
Y
G
R
V
T
A
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139165
800
90747
V666
G
V
V
P
Q
D
T
V
L
F
N
D
N
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650503
866
97867
Y672
T
I
F
Y
N
I
E
Y
A
K
L
G
A
S
D
Honey Bee
Apis mellifera
XP_001122583
748
85114
N615
E
K
I
L
S
F
P
N
G
Y
E
T
Q
V
G
Nematode Worm
Caenorhab. elegans
NP_001022812
801
90557
F646
T
I
M
Y
N
I
R
F
G
R
P
D
A
S
D
Sea Urchin
Strong. purpuratus
XP_001181861
832
94582
Y673
D
I
R
Y
N
I
G
Y
G
K
T
Q
C
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
H595
A
A
R
R
A
A
I
H
E
T
I
S
N
F
P
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
K557
Q
L
A
P
L
I
K
K
L
P
Q
G
F
D
T
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
G583
N
T
K
V
G
E
R
G
L
M
I
S
G
G
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
67.7
N.A.
88.9
87.4
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
49.5
50
42.5
51.3
Protein Similarity:
100
99.6
N.A.
71.5
N.A.
93.4
92.9
N.A.
N.A.
N.A.
N.A.
74.9
N.A.
64.7
65.9
59.1
66.2
P-Site Identity:
100
100
N.A.
73.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
40
13.3
53.3
33.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
60
20
66.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
33
35.2
Protein Similarity:
N.A.
N.A.
N.A.
52.4
49.5
51.5
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
47
0
8
8
0
0
8
0
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
8
0
0
16
0
8
0
0
0
0
0
16
0
8
39
% D
% Glu:
8
0
0
0
0
8
8
0
8
0
8
0
0
0
8
% E
% Phe:
0
0
8
0
0
8
0
8
0
8
0
0
8
8
0
% F
% Gly:
8
0
0
0
8
0
8
8
62
0
0
16
8
47
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
62
8
0
0
70
8
0
0
0
24
0
0
8
0
% I
% Lys:
0
8
8
0
0
0
8
8
0
16
0
0
0
0
0
% K
% Leu:
0
8
0
8
8
0
0
0
24
0
8
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
24
62
0
0
8
0
0
8
0
16
0
16
% N
% Pro:
0
0
0
16
0
0
8
0
0
8
8
0
0
0
8
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
8
8
8
0
0
% Q
% Arg:
0
0
16
8
0
0
54
0
0
39
0
0
0
0
8
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
16
0
24
0
% S
% Thr:
54
8
0
0
0
0
8
0
0
8
8
47
0
0
16
% T
% Val:
0
8
8
8
0
0
0
8
0
0
31
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
24
0
0
0
54
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _