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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC40A1 All Species: 23.33
Human Site: S403 Identified Species: 57.04
UniProt: Q9NP59 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP59 NP_055400.1 571 62542 S403 S P L D L S V S P F E D I R S
Chimpanzee Pan troglodytes XP_515981 645 70295 S477 S P L D L S V S P F E D I R S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535999 576 62866 S403 S P L D L S V S P F E D I R S
Cat Felis silvestris
Mouse Mus musculus Q9JHI9 570 62684 S403 S P L D L S V S P F E D I R S
Rat Rattus norvegicus Q923U9 570 62568 S403 S P L D L S V S P F E D I R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515338 499 54059 T351 T T L A P L M T T P N G L L W
Chicken Gallus gallus
Frog Xenopus laevis NP_001086826 576 62846 S405 S A L D L S V S P F A D I S T
Zebra Danio Brachydanio rerio Q9I9R3 562 61743 E400 D L S V S P F E E V L R H L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782524 601 65126 G433 S P F I Y D Y G N S T I D A S
Poplar Tree Populus trichocarpa XP_002323640 343 38414 G195 L L A P V I S G F I M S F I S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.5 N.A. 91.6 N.A. 90 90 N.A. 59.7 N.A. 75.6 67.5 N.A. N.A. N.A. N.A. 38.6
Protein Similarity: 100 88.5 N.A. 94.9 N.A. 93.1 93.3 N.A. 68.6 N.A. 86.1 79.5 N.A. N.A. N.A. N.A. 56.2
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 6.6 N.A. 73.3 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 33.3 N.A. 80 0 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 22 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 0 0 0 0 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 60 0 10 0 0 0 0 0 60 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 10 0 50 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 10 0 10 60 0 0 10 0 10 % F
% Gly: 0 0 0 0 0 0 0 20 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 10 0 10 0 0 0 10 0 10 60 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 20 70 0 60 10 0 0 0 0 10 0 10 20 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % N
% Pro: 0 60 0 10 10 10 0 0 60 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 50 0 % R
% Ser: 70 0 10 0 10 60 10 60 0 10 0 10 0 10 70 % S
% Thr: 10 10 0 0 0 0 0 10 10 0 10 0 0 0 10 % T
% Val: 0 0 0 10 10 0 60 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _