Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC40A1 All Species: 10.3
Human Site: T421 Identified Species: 25.19
UniProt: Q9NP59 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP59 NP_055400.1 571 62542 T421 Q G E S I T P T K I P E I T T
Chimpanzee Pan troglodytes XP_515981 645 70295 T495 Q G E S I T P T K I P E I T T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535999 576 62866 M421 Q A E P L S T M T P T K V P E
Cat Felis silvestris
Mouse Mus musculus Q9JHI9 570 62684 T421 N V E P V S P T T K I P E T V
Rat Rattus norvegicus Q923U9 570 62568 T421 H E E A V S S T T K I P E T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515338 499 54059 P369 S D L P S P T P Q A S P Q P V
Chicken Gallus gallus
Frog Xenopus laevis NP_001086826 576 62846 M423 E G E T L P T M S P V P D V Y
Zebra Danio Brachydanio rerio Q9I9R3 562 61743 T418 G S L R E S P T F I P T T E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782524 601 65126 T451 S P P L T L T T P H V G V M A
Poplar Tree Populus trichocarpa XP_002323640 343 38414 W213 S A M T L A V W N T V A V W L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.5 N.A. 91.6 N.A. 90 90 N.A. 59.7 N.A. 75.6 67.5 N.A. N.A. N.A. N.A. 38.6
Protein Similarity: 100 88.5 N.A. 94.9 N.A. 93.1 93.3 N.A. 68.6 N.A. 86.1 79.5 N.A. N.A. N.A. N.A. 56.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 26.6 20 N.A. 0 N.A. 13.3 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 40 N.A. 40 40 N.A. 6.6 N.A. 33.3 33.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 22 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 10 0 10 0 0 0 10 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 10 10 60 0 10 0 0 0 0 0 0 20 20 10 20 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 30 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 20 0 0 0 0 30 20 0 20 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 20 20 0 10 0 0 0 % K
% Leu: 0 0 20 10 30 10 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 10 0 0 0 0 20 0 0 0 0 0 10 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 10 30 0 20 40 10 10 20 30 40 0 20 10 % P
% Gln: 30 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 30 10 0 20 10 40 10 0 10 0 10 0 0 0 0 % S
% Thr: 0 0 0 20 10 20 40 60 30 10 10 10 10 40 20 % T
% Val: 0 10 0 0 20 0 10 0 0 0 30 0 30 10 20 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _