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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC40A1
All Species:
10
Human Site:
T445
Identified Species:
24.44
UniProt:
Q9NP59
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP59
NP_055400.1
571
62542
T445
S
A
N
I
V
P
E
T
S
P
E
S
V
P
I
Chimpanzee
Pan troglodytes
XP_515981
645
70295
T519
S
A
N
I
V
P
E
T
S
P
E
S
V
P
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535999
576
62866
G445
S
N
G
S
D
P
A
G
I
F
P
E
T
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI9
570
62684
S445
M
S
N
V
H
E
M
S
T
K
P
I
P
I
V
Rat
Rattus norvegicus
Q923U9
570
62568
S445
V
N
T
V
H
E
M
S
T
K
S
V
P
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515338
499
54059
I393
A
G
V
I
A
A
R
I
G
L
W
S
F
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086826
576
62846
S447
N
N
S
T
S
Q
F
S
D
S
E
A
G
V
S
Zebra Danio
Brachydanio rerio
Q9I9R3
562
61743
S442
E
E
A
P
P
V
E
S
Y
M
S
V
G
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782524
601
65126
V475
Q
A
P
D
L
S
R
V
Q
C
K
Y
T
G
T
Poplar Tree
Populus trichocarpa
XP_002323640
343
38414
E237
T
G
I
P
A
L
A
E
S
S
Q
R
R
I
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
91.6
N.A.
90
90
N.A.
59.7
N.A.
75.6
67.5
N.A.
N.A.
N.A.
N.A.
38.6
Protein Similarity:
100
88.5
N.A.
94.9
N.A.
93.1
93.3
N.A.
68.6
N.A.
86.1
79.5
N.A.
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
100
N.A.
13.3
N.A.
6.6
6.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
13.3
N.A.
40
26.6
N.A.
26.6
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
22
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
10
0
20
10
20
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
10
10
0
0
0
20
30
10
0
0
30
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% F
% Gly:
0
20
10
0
0
0
0
10
10
0
0
0
20
10
0
% G
% His:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
30
0
0
0
10
10
0
0
10
0
30
30
% I
% Lys:
0
0
0
0
0
0
0
0
0
20
10
0
0
0
0
% K
% Leu:
0
0
0
0
10
10
0
0
0
10
0
0
0
10
20
% L
% Met:
10
0
0
0
0
0
20
0
0
10
0
0
0
0
0
% M
% Asn:
10
30
30
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
20
10
30
0
0
0
20
20
0
20
20
10
% P
% Gln:
10
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
0
10
10
0
0
% R
% Ser:
30
10
10
10
10
10
0
40
30
20
20
30
0
0
20
% S
% Thr:
10
0
10
10
0
0
0
20
20
0
0
0
20
10
10
% T
% Val:
10
0
10
20
20
10
0
10
0
0
0
20
20
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _