Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB18 All Species: 42.73
Human Site: S144 Identified Species: 55.29
UniProt: Q9NP72 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.12
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP72 NP_067075.1 206 22977 S144 L K F A R K H S M L F I E A S
Chimpanzee Pan troglodytes XP_507716 449 49628 S387 L K F A R K H S M L F I E A S
Rhesus Macaque Macaca mulatta XP_001104913 235 26392 S173 L K F A R K H S M L F I E A S
Dog Lupus familis XP_848769 206 22974 S144 L K F A R K H S M L F I E A S
Cat Felis silvestris
Mouse Mus musculus P35293 206 23017 S144 L K F A R K H S M L F I E A S
Rat Rattus norvegicus Q5EB77 206 22958 S144 L K F A R K H S M L F I E A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506607 206 22923 S144 L K F A R K H S M L F I E A S
Chicken Gallus gallus Q5ZLG1 206 22936 S144 L K F A R K H S M L F I E A S
Frog Xenopus laevis NP_001079868 205 22995 S144 L K F A R K H S M L Y I E A S
Zebra Danio Brachydanio rerio Q6DHC1 205 22995 S144 L K F A R K H S M L F I E A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392903 223 25432 Q146 L Q F A R R H Q T L Y I E S S
Nematode Worm Caenorhab. elegans Q8MXS1 203 22601 R132 N K I D M P N R V V T R E E G
Sea Urchin Strong. purpuratus XP_001181010 168 18914 I110 R K H S C L F I E C S A K T R
Poplar Tree Populus trichocarpa XP_002306250 209 23323 G150 I N F A R E Y G C L F I E C S
Maize Zea mays P49104 210 23043 G142 E Q F A K E H G L I F M E A S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28188 203 22630 G144 K A F A D E I G I P F M E T S
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 K144 K E F A D A N K M P F L E T S
Red Bread Mold Neurospora crassa P33723 203 22458 T134 D K K V V E Y T V A K E F A D
Conservation
Percent
Protein Identity: 100 44.9 87.6 98.5 N.A. 99 98.5 N.A. 97 97 89.8 88.3 N.A. N.A. 56.5 66 59.7
Protein Similarity: 100 45.8 87.6 99.5 N.A. 99.5 98.5 N.A. 97.5 99 93.1 94.1 N.A. N.A. 72.1 79.1 67.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. N.A. 60 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. 86.6 33.3 20
Percent
Protein Identity: 57.4 45.2 N.A. 42.7 44.6 44.6
Protein Similarity: 70.3 62.3 N.A. 59.7 63.5 59.7
P-Site Identity: 53.3 46.6 N.A. 33.3 40 13.3
P-Site Similarity: 73.3 86.6 N.A. 53.3 60 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 84 0 6 0 0 0 6 0 6 0 67 0 % A
% Cys: 0 0 0 0 6 0 0 0 6 6 0 0 0 6 0 % C
% Asp: 6 0 0 6 12 0 0 0 0 0 0 0 0 0 6 % D
% Glu: 6 6 0 0 0 23 0 0 6 0 0 6 89 6 0 % E
% Phe: 0 0 84 0 0 0 6 0 0 0 73 0 6 0 0 % F
% Gly: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 6 % G
% His: 0 0 6 0 0 0 67 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 6 0 0 0 6 6 6 6 0 67 0 0 0 % I
% Lys: 12 73 6 0 6 56 0 6 0 0 6 0 6 0 0 % K
% Leu: 62 0 0 0 0 6 0 0 6 67 0 6 0 0 0 % L
% Met: 0 0 0 0 6 0 0 0 62 0 0 12 0 0 0 % M
% Asn: 6 6 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 6 0 0 0 12 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 0 0 6 0 0 0 0 0 0 0 % Q
% Arg: 6 0 0 0 67 6 0 6 0 0 0 6 0 0 6 % R
% Ser: 0 0 0 6 0 0 0 56 0 0 6 0 0 6 84 % S
% Thr: 0 0 0 0 0 0 0 6 6 0 6 0 0 17 0 % T
% Val: 0 0 0 6 6 0 0 0 12 6 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _