KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA8
All Species:
15.15
Human Site:
S234
Identified Species:
37.04
UniProt:
Q9NP80
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP80
NP_056538.1
782
88477
S234
N
E
H
F
R
D
K
S
E
L
E
D
K
K
V
Chimpanzee
Pan troglodytes
XP_001166265
782
88516
S234
N
E
H
F
R
D
K
S
E
L
E
D
K
K
V
Rhesus Macaque
Macaca mulatta
XP_001096331
782
88385
S234
N
E
H
F
Q
D
K
S
K
L
E
D
K
E
V
Dog
Lupus familis
XP_848649
784
88284
S235
N
K
H
F
Q
E
K
S
E
L
E
D
K
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1N1
776
87363
L234
Q
L
Q
D
K
P
D
L
E
E
R
K
S
S
S
Rat
Rattus norvegicus
NP_001101490
400
45630
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124209
803
90680
K255
Q
G
S
K
S
E
T
K
L
D
S
S
E
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001918731
696
76918
P173
V
P
Q
A
P
S
I
P
V
Q
D
E
G
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500969
546
60511
I23
L
R
R
H
P
S
T
I
D
G
L
T
P
E
R
Sea Urchin
Strong. purpuratus
XP_782958
927
103360
S349
L
E
K
D
K
A
T
S
K
I
T
T
S
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.6
89.6
N.A.
82.3
37.4
N.A.
N.A.
60.1
N.A.
47.8
N.A.
N.A.
N.A.
29.4
32.9
Protein Similarity:
100
99.8
98.5
94.6
N.A.
90.6
43.3
N.A.
N.A.
73.5
N.A.
63.8
N.A.
N.A.
N.A.
43.7
51.2
P-Site Identity:
100
100
80
80
N.A.
6.6
0
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
0
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
30
10
0
10
10
10
40
0
0
0
% D
% Glu:
0
40
0
0
0
20
0
0
40
10
40
10
10
20
0
% E
% Phe:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
40
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
10
0
0
0
0
0
% I
% Lys:
0
10
10
10
20
0
40
10
20
0
0
10
40
30
0
% K
% Leu:
20
10
0
0
0
0
0
10
10
40
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% N
% Pro:
0
10
0
0
20
10
0
10
0
0
0
0
10
0
0
% P
% Gln:
20
0
20
0
20
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
10
10
0
20
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
0
0
10
0
10
20
0
50
0
0
10
10
20
10
20
% S
% Thr:
0
0
0
0
0
0
30
0
0
0
10
20
0
0
10
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _