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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA8
All Species:
20.61
Human Site:
T670
Identified Species:
50.37
UniProt:
Q9NP80
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP80
NP_056538.1
782
88477
T670
Y
E
S
D
V
R
N
T
V
T
Y
T
S
L
K
Chimpanzee
Pan troglodytes
XP_001166265
782
88516
T670
Y
E
S
D
V
R
N
T
V
T
Y
T
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001096331
782
88385
T670
Y
E
S
D
V
R
N
T
V
T
H
T
S
L
K
Dog
Lupus familis
XP_848649
784
88284
S672
Y
E
S
D
V
R
N
S
V
T
S
T
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1N1
776
87363
T664
Y
E
S
D
V
R
N
T
S
T
Y
T
S
L
K
Rat
Rattus norvegicus
NP_001101490
400
45630
G291
F
L
S
R
P
T
E
G
V
Q
A
L
V
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124209
803
90680
N691
Y
E
S
A
G
K
T
N
V
T
Y
T
S
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001918731
696
76918
Y587
T
K
T
S
A
S
T
Y
T
S
L
K
T
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500969
546
60511
T437
T
S
V
E
P
T
P
T
V
F
S
T
S
F
Q
Sea Urchin
Strong. purpuratus
XP_782958
927
103360
P816
L
G
T
G
R
Y
D
P
M
E
E
G
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.6
89.6
N.A.
82.3
37.4
N.A.
N.A.
60.1
N.A.
47.8
N.A.
N.A.
N.A.
29.4
32.9
Protein Similarity:
100
99.8
98.5
94.6
N.A.
90.6
43.3
N.A.
N.A.
73.5
N.A.
63.8
N.A.
N.A.
N.A.
43.7
51.2
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
13.3
N.A.
N.A.
66.6
N.A.
0
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
N.A.
73.3
N.A.
26.6
N.A.
N.A.
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
60
0
10
0
0
10
0
0
10
10
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
10
0
10
10
0
0
10
0
0
0
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
0
0
0
10
0
10
60
% K
% Leu:
10
10
0
0
0
0
0
0
0
0
10
10
10
60
20
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
50
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
10
10
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
70
10
0
10
0
10
10
10
20
0
70
0
0
% S
% Thr:
20
0
20
0
0
20
20
50
10
60
0
70
10
0
0
% T
% Val:
0
0
10
0
50
0
0
0
70
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
0
10
0
10
0
0
40
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _