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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SARS2 All Species: 12.73
Human Site: T259 Identified Species: 28
UniProt: Q9NP81 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP81 NP_001139373.1 518 58283 T259 R R G F T P M T V P D L L R G
Chimpanzee Pan troglodytes XP_001162887 327 35685 M77 A V F E G C G M T P N A N P S
Rhesus Macaque Macaca mulatta XP_001085926 509 56991 V251 A G F T P M T V P D L L R G A
Dog Lupus familis XP_541632 518 58305 T259 H R G F T P M T V P D L L R G
Cat Felis silvestris
Mouse Mus musculus Q9JJL8 518 58284 T259 S R G F T P M T V P D L L R G
Rat Rattus norvegicus NP_001099710 518 58268 T259 S R G F T P M T V P D L L R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957473 510 57624 V259 K R G F I P M V V P D I L K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788714 508 57881 I258 I K N H G F K I I K V P D L I
Poplar Tree Populus trichocarpa XP_002301073 523 58040 K270 W T L S E V M K K G F T P L T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172651 512 57163 K259 W T L S Q V M K K G Y T P L T
Baker's Yeast Sacchar. cerevisiae P38705 446 50371 V196 A R L E Q A L V A Y A L K K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 85.1 86.6 N.A. 85.9 86.2 N.A. N.A. N.A. N.A. 55.7 N.A. N.A. N.A. N.A. 38.4
Protein Similarity: 100 48 87.4 92.2 N.A. 92.4 91.8 N.A. N.A. N.A. N.A. 72 N.A. N.A. N.A. N.A. 58.1
P-Site Identity: 100 6.6 6.6 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 60 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 6.6 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 80 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 31.5 N.A. N.A. 32 28.9 N.A.
Protein Similarity: 50.1 N.A. N.A. 52.3 50.5 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 6.6 N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 0 0 0 10 0 0 10 0 10 10 0 0 19 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 46 0 10 0 0 % D
% Glu: 0 0 0 19 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 19 46 0 10 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 46 0 19 0 10 0 0 19 0 0 0 10 37 % G
% His: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 0 10 10 0 0 10 0 0 10 % I
% Lys: 10 10 0 0 0 0 10 19 19 10 0 0 10 19 0 % K
% Leu: 0 0 28 0 0 0 10 0 0 0 10 55 46 28 0 % L
% Met: 0 0 0 0 0 10 64 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 10 0 10 0 0 % N
% Pro: 0 0 0 0 10 46 0 0 10 55 0 10 19 10 0 % P
% Gln: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 55 0 0 0 0 0 0 0 0 0 0 10 37 0 % R
% Ser: 19 0 0 19 0 0 0 0 0 0 0 0 0 0 19 % S
% Thr: 0 19 0 10 37 0 10 37 10 0 0 19 0 0 19 % T
% Val: 0 10 0 0 0 19 0 28 46 0 10 0 0 0 0 % V
% Trp: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _