KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS2
All Species:
20.91
Human Site:
S352
Identified Species:
38.33
UniProt:
Q9NP85
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP85
NP_055440.1
383
42201
S352
D
L
L
N
C
L
S
S
P
S
N
R
T
Q
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090776
288
31597
T258
R
Y
L
Q
T
L
T
T
I
A
A
E
K
N
S
Dog
Lupus familis
XP_547443
542
59797
S511
D
L
L
N
F
L
S
S
P
G
N
R
T
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91X05
385
42318
S354
D
M
L
S
L
L
S
S
P
G
N
R
A
Q
G
Rat
Rattus norvegicus
Q8K4G9
383
42368
S352
D
M
L
N
L
L
S
S
P
S
N
R
A
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515734
392
44086
S361
D
L
L
N
L
L
S
S
A
G
N
K
T
Q
G
Chicken
Gallus gallus
XP_422265
382
42762
S351
D
P
T
N
L
V
S
S
A
T
R
S
P
P
G
Frog
Xenopus laevis
NP_001080862
281
30963
Y251
P
S
A
L
Q
L
R
Y
L
Q
T
L
T
T
I
Zebra Danio
Brachydanio rerio
NP_001018155
390
43665
Q359
I
P
P
D
V
L
T
Q
S
I
D
L
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZA4
505
57508
K425
D
L
I
T
Y
F
L
K
T
N
E
A
T
T
Q
Honey Bee
Apis mellifera
XP_001123020
273
30388
T243
R
Y
L
Q
T
L
N
T
I
S
A
E
K
N
S
Nematode Worm
Caenorhab. elegans
Q27433
481
51881
Q368
D
L
L
S
A
F
L
Q
R
T
P
P
K
V
E
Sea Urchin
Strong. purpuratus
XP_783694
283
31056
R253
S
P
A
A
L
Q
L
R
Y
L
Q
T
L
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
38.1
58.4
N.A.
85.9
85.1
N.A.
74.7
61.8
39.1
44.8
N.A.
32
35.7
32.2
38.3
Protein Similarity:
100
N.A.
55
63.4
N.A.
91.4
91.6
N.A.
83.4
75.1
55.3
62.5
N.A.
49.1
53
50.3
55
P-Site Identity:
100
N.A.
13.3
86.6
N.A.
66.6
80
N.A.
73.3
33.3
13.3
6.6
N.A.
20
20
20
0
P-Site Similarity:
100
N.A.
33.3
86.6
N.A.
80
86.6
N.A.
80
46.6
13.3
26.6
N.A.
33.3
33.3
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
0
0
0
16
8
16
8
24
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
16
0
0
8
% E
% Phe:
0
0
0
0
8
16
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
47
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
16
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
8
24
0
0
% K
% Leu:
0
39
62
8
39
70
24
0
8
8
0
16
8
0
8
% L
% Met:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
39
0
0
8
0
0
8
39
0
0
24
0
% N
% Pro:
8
24
8
0
0
0
0
0
31
0
8
8
8
8
0
% P
% Gln:
0
0
0
16
8
8
0
16
0
8
8
0
0
39
8
% Q
% Arg:
16
0
0
0
0
0
8
8
8
0
8
31
0
0
0
% R
% Ser:
8
8
0
16
0
0
47
47
8
24
0
8
0
8
16
% S
% Thr:
0
0
8
8
16
0
16
16
8
16
8
8
39
16
8
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
8
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _