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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS2
All Species:
5.45
Human Site:
S367
Identified Species:
10
UniProt:
Q9NP85
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP85
NP_055440.1
383
42201
S367
S
L
P
F
P
S
P
S
K
P
V
E
P
L
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090776
288
31597
I273
T
I
V
F
P
L
P
I
D
M
L
Q
G
I
I
Dog
Lupus familis
XP_547443
542
59797
A526
S
L
P
F
P
S
P
A
K
P
V
E
P
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91X05
385
42318
S369
S
I
N
Y
P
S
S
S
K
P
V
E
P
L
N
Rat
Rattus norvegicus
Q8K4G9
383
42368
P367
S
I
N
Y
P
S
S
P
K
P
V
E
P
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515734
392
44086
P376
S
I
P
F
P
H
P
P
K
L
P
E
P
A
D
Chicken
Gallus gallus
XP_422265
382
42762
T366
V
N
S
I
I
T
D
T
T
E
L
R
E
S
V
Frog
Xenopus laevis
NP_001080862
281
30963
I266
A
S
E
K
N
S
T
I
V
F
P
L
P
I
D
Zebra Danio
Brachydanio rerio
NP_001018155
390
43665
M374
T
R
P
A
N
Q
S
M
T
T
C
D
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZA4
505
57508
A440
Q
N
A
R
A
A
A
A
A
I
G
N
T
P
P
Honey Bee
Apis mellifera
XP_001123020
273
30388
I258
T
I
V
F
P
L
P
I
D
L
L
T
Y
F
M
Nematode Worm
Caenorhab. elegans
Q27433
481
51881
K383
E
P
P
S
L
P
K
K
I
R
S
C
C
L
Y
Sea Urchin
Strong. purpuratus
XP_783694
283
31056
T268
I
S
A
E
K
N
S
T
I
I
F
P
L
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
38.1
58.4
N.A.
85.9
85.1
N.A.
74.7
61.8
39.1
44.8
N.A.
32
35.7
32.2
38.3
Protein Similarity:
100
N.A.
55
63.4
N.A.
91.4
91.6
N.A.
83.4
75.1
55.3
62.5
N.A.
49.1
53
50.3
55
P-Site Identity:
100
N.A.
20
86.6
N.A.
73.3
66.6
N.A.
53.3
0
13.3
6.6
N.A.
0
20
13.3
0
P-Site Similarity:
100
N.A.
53.3
93.3
N.A.
86.6
80
N.A.
66.6
20
33.3
26.6
N.A.
13.3
40
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
8
8
8
16
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
16
0
0
8
0
0
24
% D
% Glu:
8
0
8
8
0
0
0
0
0
8
0
39
8
0
0
% E
% Phe:
0
0
0
39
0
0
0
0
0
8
8
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
16
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
39
0
8
8
0
0
24
16
16
0
0
0
16
16
% I
% Lys:
0
0
0
8
8
0
8
8
39
0
0
0
0
0
0
% K
% Leu:
0
16
0
0
8
16
0
0
0
16
24
8
8
31
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% M
% Asn:
0
16
16
0
16
8
0
0
0
0
0
8
0
0
31
% N
% Pro:
0
8
39
0
54
8
39
16
0
31
16
8
47
24
8
% P
% Gln:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
39
16
8
8
0
39
31
16
0
0
8
0
0
16
0
% S
% Thr:
24
0
0
0
0
8
8
16
16
8
0
8
8
0
0
% T
% Val:
8
0
16
0
0
0
0
0
8
0
31
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _