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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPHS2 All Species: 0
Human Site: S48 Identified Species: 0
UniProt: Q9NP85 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP85 NP_055440.1 383 42201 S48 A G P E P S G S G R A G T P G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090776 288 31597
Dog Lupus familis XP_547443 542 59797 E207 G P E E H G K E R R H P T K H
Cat Felis silvestris
Mouse Mus musculus Q91X05 385 42318 R50 A E R Q S T G R T A T R G E P
Rat Rattus norvegicus Q8K4G9 383 42368 A48 A G A E R Q S A G R T G T R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515734 392 44086 E57 R V K E D K K E T R S T L E V
Chicken Gallus gallus XP_422265 382 42762 K48 D I R Q G K T K E I K S T V G
Frog Xenopus laevis NP_001080862 281 30963
Zebra Danio Brachydanio rerio NP_001018155 390 43665 E59 K E K P A T T E E E E A K D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZA4 505 57508 M121 Q Q Q Q Q Q Q M M Q Q P Q Q Q
Honey Bee Apis mellifera XP_001123020 273 30388
Nematode Worm Caenorhab. elegans Q27433 481 51881 M64 S S D E V E N M A T R T L Q Q
Sea Urchin Strong. purpuratus XP_783694 283 31056
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 38.1 58.4 N.A. 85.9 85.1 N.A. 74.7 61.8 39.1 44.8 N.A. 32 35.7 32.2 38.3
Protein Similarity: 100 N.A. 55 63.4 N.A. 91.4 91.6 N.A. 83.4 75.1 55.3 62.5 N.A. 49.1 53 50.3 55
P-Site Identity: 100 N.A. 0 20 N.A. 13.3 46.6 N.A. 13.3 13.3 0 0 N.A. 0 0 6.6 0
P-Site Similarity: 100 N.A. 0 20 N.A. 26.6 53.3 N.A. 20 20 0 6.6 N.A. 13.3 0 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 8 0 8 0 0 8 8 8 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 8 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 16 8 39 0 8 0 24 16 8 8 0 0 16 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 16 0 0 8 8 16 0 16 0 0 16 8 0 16 % G
% His: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 8 % H
% Ile: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 8 0 16 0 0 16 16 8 0 0 8 0 8 8 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 16 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 8 8 0 0 0 0 0 0 16 0 8 8 % P
% Gln: 8 8 8 24 8 16 8 0 0 8 8 0 8 16 16 % Q
% Arg: 8 0 16 0 8 0 0 8 8 31 8 8 0 8 0 % R
% Ser: 8 8 0 0 8 8 8 8 0 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 16 16 0 16 8 16 16 31 0 0 % T
% Val: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _