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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS2
All Species:
16.06
Human Site:
S86
Identified Species:
29.44
UniProt:
Q9NP85
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP85
NP_055440.1
383
42201
S86
E
V
V
A
L
L
E
S
E
R
P
E
E
G
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090776
288
31597
G26
F
K
D
S
P
S
K
G
L
G
P
C
G
W
I
Dog
Lupus familis
XP_547443
542
59797
F245
A
R
E
A
R
S
G
F
L
W
P
R
K
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91X05
385
42318
S88
E
V
V
A
L
L
E
S
E
R
P
E
E
G
I
Rat
Rattus norvegicus
Q8K4G9
383
42368
S86
E
V
V
A
L
L
E
S
E
R
P
E
E
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515734
392
44086
S95
E
V
M
A
L
L
E
S
E
R
Q
E
E
G
I
Chicken
Gallus gallus
XP_422265
382
42762
E86
A
M
M
L
L
D
S
E
H
Q
E
E
G
M
K
Frog
Xenopus laevis
NP_001080862
281
30963
I19
G
N
Q
E
S
S
N
I
T
V
S
E
G
G
L
Zebra Danio
Brachydanio rerio
NP_001018155
390
43665
T97
E
L
L
A
L
L
E
T
E
G
P
G
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZA4
505
57508
E159
Q
Q
A
I
H
R
A
E
A
R
R
A
D
E
E
Honey Bee
Apis mellifera
XP_001123020
273
30388
N11
V
D
E
N
V
Q
T
N
N
D
T
C
K
N
I
Nematode Worm
Caenorhab. elegans
Q27433
481
51881
N102
E
K
D
V
E
K
G
N
G
K
E
E
K
A
N
Sea Urchin
Strong. purpuratus
XP_783694
283
31056
G21
D
G
Q
V
E
V
I
G
A
N
A
S
E
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
38.1
58.4
N.A.
85.9
85.1
N.A.
74.7
61.8
39.1
44.8
N.A.
32
35.7
32.2
38.3
Protein Similarity:
100
N.A.
55
63.4
N.A.
91.4
91.6
N.A.
83.4
75.1
55.3
62.5
N.A.
49.1
53
50.3
55
P-Site Identity:
100
N.A.
6.6
20
N.A.
93.3
93.3
N.A.
80
13.3
13.3
60
N.A.
6.6
0
13.3
13.3
P-Site Similarity:
100
N.A.
20
26.6
N.A.
93.3
93.3
N.A.
86.6
33.3
13.3
80
N.A.
20
20
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
47
0
0
8
0
16
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
8
8
16
0
0
8
0
0
0
8
0
0
8
0
0
% D
% Glu:
47
0
16
8
16
0
39
16
39
0
16
54
47
8
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
16
16
8
16
0
8
24
54
8
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
39
% I
% Lys:
0
16
0
0
0
8
8
0
0
8
0
0
24
0
8
% K
% Leu:
0
8
8
8
47
39
0
0
16
0
0
0
0
0
16
% L
% Met:
0
8
16
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
8
0
0
8
16
8
8
0
0
0
8
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
47
0
0
0
0
% P
% Gln:
8
8
16
0
0
8
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
8
0
0
8
8
0
0
0
39
8
8
0
0
0
% R
% Ser:
0
0
0
8
8
24
8
31
0
0
8
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
8
8
8
0
8
0
0
0
16
% T
% Val:
8
31
24
16
8
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _